Interactor 1: SKI (P12755)
Ski oncogene (Proto-oncogene c-Ski)
Gene: SKI

Interactor 2: TGFR1 (P36897)
TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)
Gene: TGFBR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 20959473
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0031625 - ubiquitin protein ligase binding
GO:0046332 - SMAD binding
GO:0048870 - cell motility
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 728
Hs

1 503
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024