HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: RBP56 (Q92804)
TATA-binding protein-associated factor 2N (68 kDa TATA-binding protein-associated factor) (TAF(II)68) (TAFII68) (RNA-binding protein 56)
Gene: TAF15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008270 - zinc ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 592
+	Hs
		400677 RAF1_HUMAN (1-648): 0: 637: 100.00		EWS_HUMAN (4-383): 3.75e-35: 142: 32.96
+	Hs
		401739 RAF1_HUMAN (1-648): 0: 637: 100.00		RBMX2_HUMAN (227-440): 6.27e-28: 116: 19.36
+	Hs
		400820 RAF1_HUMAN (1-648): 0: 637: 100.00		EIF3A_HUMAN (314-591): 5.43e-22: 103: 18.21
+	Hs
		400205 RAF1_HUMAN (1-648): 0: 637: 100.00		COBA1_HUMAN (14-525): 2.32e-18: 91.8: 12.02
+	Hs
		400117 RAF1_HUMAN (1-648): 0: 637: 100.00		CO5A2_HUMAN (316-592): 1.19e-10: 66.8: 20.42
+	Hs
		384227 RAF1_HUMAN (1-648): 0: 637: 100.00		CO2A1_HUMAN (294-590): 1.38e-09: 63.3: 16.08
+	Hs
		521399 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		RBP56_HUMAN (1-394): 5.2e-37: 147: 100.00
+	Hs
		521316 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		EWS_HUMAN (4-383): 3.75e-35: 142: 32.96
+	Hs
		521228 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		FUS_HUMAN (8-381): 2.74e-32: 132: 39.28
+	Hs
		225246 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		HTSF1_HUMAN (113-325): 5.61e-31: 130: 18.06