HitPredict

Interactor 1: H14 (P10412)
Histone H1.4 (Histone H1b) (Histone H1s-4)
Gene: H1-4

Interactor 2: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.954

The method score is based on:

Property Details
Experiments 34349018, 35235311, 30021884, 35575683, 38334954, 39358380, 39422127
Identification Methods cross-linking study, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Linker_histone~Linker_histone
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000786 - nucleosome
GO:0000791 - euchromatin
GO:0003690 - double-stranded DNA binding
GO:0003723 - RNA binding
and 7 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 219
Hs

1 213
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025