HitPredict

Interactor 1: BCL3 (P20749)
B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3)
Gene: BCL3

Interactor 2: KAT5 (Q92993)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein)
Gene: KAT5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

The method score is based on:

Property	Details
Experiments	10362352, 15829968
Identification Methods	two hybrid, pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 8 others more... GO:0006974 - DNA damage response GO:0042981 - regulation of apoptotic process GO:0043231 - intracellular membrane-bounded organelle GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0048471 - perinuclear region of cytoplasm GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	454
Hs

1	513

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024