HitPredict

Interactor 1: ACTN1 (P12814)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26496610, 31586073, 36526897
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 892 Hs			1 1124
+	Hs
		211670 ACTN4_HUMAN (11-892): 0: 642: 86.74		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		993298 ACTN3_HUMAN (18-892): 0: 642: 78.51		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		725703 ACTN2_HUMAN (10-892): 0: 640: 80.29		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		164668 SPTN2_HUMAN (225-763): 1.02e-15: 84.3: 14.42		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		963430 SPTB2_HUMAN (196-761): 3.97e-14: 79.3: 12.17		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		506845 SPTB1_HUMAN (235-847): 3.12e-09: 63.1: 10.29		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1329040 SPTN4_HUMAN (173-588): 8.58e-09: 62: 10.82		ANLN_HUMAN (1-1124): 0: 1520: 100.00