HitPredict

Interactor 1: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Interactor 2: DDX50 (Q9BQ39)
ATP-dependent RNA helicase DDX50 (EC 3.6.4.13) (DEAD box protein 50) (Gu-beta) (Nucleolar protein Gu2)
Gene: DDX50

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 737
+	Hs
		133822 K2C6A_HUMAN (4-407): 1.22e-124: 380: 22.82		DDX3X_HUMAN (15-526): 5.63e-129: 399: 24.86
+	Hs
		133866 K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74		DDX3X_HUMAN (15-526): 5.63e-129: 399: 24.86
+	Hs
		133831 K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85		DDX3X_HUMAN (15-526): 5.63e-129: 399: 24.86
+	Hs
		595431 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		DDX21_HUMAN (20-736): 5.59e-143: 439: 59.86
+	Hs
		360450 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		DDX21_HUMAN (20-736): 5.59e-143: 439: 59.86
+	Hs
		359643 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		DDX5_HUMAN (73-588): 1.42e-137: 420: 25.58
+	Mm
		821712 LMNA_MOUSE (3-580): 4.36e-63: 221: 53.37		DDX3Y_MOUSE (15-527): 9.04e-137: 419: 25.19
+	Hs
		360112 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		DDX42_HUMAN (8-732): 1.01e-127: 404: 20.18
+	Hs
		133823 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		DDX3X_HUMAN (15-526): 5.63e-129: 399: 24.86
+	Ce
		1094229 LMN1_CAEEL (28-549): 1.7e-58: 206: 32.01		Q65XX1_CAEEL (162-498): 8.78e-56: 204: 34.38
+	Ce
		1094235 LMN1_CAEEL (28-549): 1.7e-58: 206: 32.01		Q95XY1_CAEEL (162-498): 1.4e-55: 203: 34.38
+	Ce
		1094241 LMN1_CAEEL (28-549): 1.7e-58: 206: 32.01		Q9N3F4_CAEEL (162-498): 1.09e-55: 203: 34.38