Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 10910767, 10202138, 9700170, 12370292, 19114658, 19646884, 21300292, 23112161, 24725409
Identification Methods biochemical, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, bead aggregation assay, fluorescent resonance energy transfer, cross-linking study, atomic force microscopy, tandem affinity purification, force spectroscopy
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cadherin~Cadherin
Common GO terms GO:0000902 - cell morphogenesis
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005768 - endosome
GO:0005802 - trans-Golgi network
and 44 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 882
Hs

1 882
+ Cl
+ Mm
+ Hs
+ Mm
+ Hs
+ Dr
+ Xl
+ Hs
+ Gg
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024