Protein: PRAM
PML-RARA-regulated adapter molecule 1 (PRAM) (PRAM-1)

Gene: PRAM, PRAM1
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q96QH2

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0007229 - integrin-mediated signaling pathway
GO:0008289 - lipid binding
GO:0019901 - protein kinase binding
GO:0032991 - protein-containing complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1292801

SKAP1
Src kinase-associated phosphoprotein 1

4

9

High-throughput

0.698

High

900470

FXR2
RNA-binding protein FXR2

4

3

High-throughput

0.637

High

1180014

CCD57
Coiled-coil domain-containing protein 57

3

9

High-throughput

0.616

High

942832

BCAR1
Breast cancer anti-estrogen resistance protein 1

2

16

High-throughput

0.606

High

1063549

GOGA2
Golgin subfamily A member 2

2

9

High-throughput

0.606

High

1127367

CASL
Enhancer of filamentation 1

2

12

High-throughput

0.606

High

572149

TRI27
Zinc finger protein RFP

2

2

Small-scale

0.592

High

188343

HDAC3
Histone deacetylase 3

2

6

Small-scale

0.584

High

520625

RARA
Retinoic acid receptor alpha

2

20

Small-scale

0.584

High

900107

FXR1
RNA-binding protein FXR1

2

3

High-throughput

0.553

High

1400900

NEK6
Serine/threonine-protein kinase Nek6

1

8

Small-scale

0.549

High

422944

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.541

High

1400904

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

7

High-throughput

0.541

High

1230216

K1C40
Keratin, type I cytoskeletal 40

1

1

High-throughput

0.523

High

1400901

ABI2
Abl interactor 2

1

12

High-throughput

0.523

High

890036

PSN1
Presenilin-1

1

0

High-throughput

0.518

High

1158485

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.518

High

384522

CRYAA
Alpha-crystallin A chain

1

5

High-throughput

0.515

High

556293

CADH1
Cadherin-1

1

3

High-throughput

0.515

High

1397282

UB2E2
Ubiquitin-conjugating enzyme E2 E2

1

2

Small-scale

0.512

High

369731

A2MG
Alpha-2-macroglobulin

1

1

High-throughput

0.494

High

1142256

CD5R1
Cyclin-dependent kinase 5 activator 1

1

0

High-throughput

0.493

High

387453

APOE
Apolipoprotein E

1

1

High-throughput

0.481

High

216521

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

5

Small-scale

0.479

High

286782

SKAP2
Src kinase-associated phosphoprotein 2

1

10

Small-scale

0.479

High

414447

P53
Cellular tumor antigen p53

1

3

Small-scale

0.479

High

463714

LYN
Tyrosine-protein kinase Lyn

1

9

Small-scale

0.479

High

675117

TNR6
Tumor necrosis factor receptor superfamily member 6

1

2

Small-scale

0.479

High

754591

S10A3
Protein S100-A3

1

3

Small-scale

0.479

High

1094315

LCP2
Lymphocyte cytosolic protein 2

1

7

Small-scale

0.479

High

1112667

CUL1
Cullin-1

1

9

Small-scale

0.479

High

521875

H14
Histone H1.4

1

8

High-throughput

0.470

High

697999

CALR
Calreticulin

1

2

High-throughput

0.470

High

788156

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

5

High-throughput

0.470

High

1053273

Q05BL1
TP53BP2 protein

1

11

High-throughput

0.470

High

1124020

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

1

High-throughput

0.470

High

1351863

NEK7
Serine/threonine-protein kinase Nek7

1

7

High-throughput

0.470

High

1369677

KLK6
Kallikrein-6

1

2

High-throughput

0.470

High

1115595

ASPP2
Apoptosis-stimulating of p53 protein 2

1

12

High-throughput

0.439

High

1280042

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

17

High-throughput

0.439

High

278406

NCOR1
Nuclear receptor corepressor 1

1

13

Small-scale

0.437

High

1033753

PO5F1
POU domain, class 5, transcription factor 1

1

5

High-throughput

0.437

High

1259630

H2AV
Histone H2A.V

1

11

High-throughput

0.437

High

1271204

DPPA4
Developmental pluripotency-associated protein 4

1

3

High-throughput

0.437

High

1313356

SMC5
Structural maintenance of chromosomes protein 5

1

8

High-throughput

0.437

High

1400897

PCGF1
Polycomb group RING finger protein 1

1

10

High-throughput

0.437

High

1400899

NANOG
Homeobox protein NANOG

1

20

High-throughput

0.437

High

1400902

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.437

High

1400903

MBD1
Methyl-CpG-binding domain protein 1

1

8

Small-scale

0.437

High

887141

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.373

High

1400898

RNF32
RING finger protein 32

1

0

High-throughput

0.296

High

1333316

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025