Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 8074697, 27684187, 14517306, 22375065, 25468996, 7542250, 9535896, 8207061, 1639850, 34591612, 9700170, 11801604, 17524503
Identification Methods pull down, affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~CADH_Y-type_LIR
Common GO terms GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0005912 - adherens junction
GO:0009898 - cytoplasmic side of plasma membrane
GO:0016342 - catenin complex
and 7 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024