Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: COF1 (P23528)
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)
Gene: CFL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 19802004
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cofilin_ADF~PK_Tyr_Ser-Thr
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0032587 - ruffle membrane
GO:0043066 - negative regulation of apoptotic process
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 536
Hs

1 166
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024