Protein: KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1 (PRPP synthase-associated protein 1) (39 kDa phosphoribosypyrophosphate synthase-associated protein) (PAP39)

Gene: KPRA, PRPSAP1
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q14558

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0002189 - ribose phosphate diphosphokinase complex
GO:0004749 - ribose phosphate diphosphokinase activity
GO:0004857 - enzyme inhibitor activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

893347

PRPS1
Ribose-phosphate pyrophosphokinase 1

13

17

Small-scale

0.985

High

515854

PRPS2
Ribose-phosphate pyrophosphokinase 2

7

17

Small-scale

0.969

High

225876

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

5

16

High-throughput

0.926

High

1055327

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

4

14

High-throughput

0.904

High

1055371

NS1BP
Influenza virus NS1A-binding protein

3

4

High-throughput

0.609

High

909562

1433E
14-3-3 protein epsilon

2

3

Small-scale

0.601

High

227452

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

181860

SOCS1
Suppressor of cytokine signaling 1

2

14

High-throughput

0.571

High

235077

DOK2
Docking protein 2

2

4

High-throughput

0.571

High

261115

SH3L1
Adapter SH3BGRL

2

3

High-throughput

0.571

High

397163

KPCG
Protein kinase C gamma type

2

15

High-throughput

0.571

High

412194

FYN
Tyrosine-protein kinase Fyn

2

10

High-throughput

0.571

High

442829

HCK
Tyrosine-protein kinase HCK

2

10

High-throughput

0.571

High

454831

FGR
Tyrosine-protein kinase Fgr

2

10

High-throughput

0.571

High

548707

VAV
Proto-oncogene vav

2

3

High-throughput

0.571

High

557692

NCK1
SH2/SH3 adapter protein NCK1

2

14

High-throughput

0.571

High

566390

KPCA
Protein kinase C alpha type

2

10

High-throughput

0.571

High

592254

RAB5A
Ras-related protein Rab-5A

2

3

High-throughput

0.571

High

596402

RASA1
Ras GTPase-activating protein 1

2

3

High-throughput

0.571

High

800777

MK08
Mitogen-activated protein kinase 8

2

5

High-throughput

0.571

High

894008

CDC42
Cell division control protein 42 homolog

2

8

High-throughput

0.571

High

925281

RAC1
Ras-related C3 botulinum toxin substrate 1

2

7

High-throughput

0.571

High

983486

PTN12
Tyrosine-protein phosphatase non-receptor type 12

2

3

High-throughput

0.571

High

1026165

PAK1
Serine/threonine-protein kinase PAK 1

2

4

High-throughput

0.571

High

1026848

MK07
Mitogen-activated protein kinase 7

2

9

High-throughput

0.571

High

1055329

KPCD1
Serine/threonine-protein kinase D1

2

14

High-throughput

0.571

High

1055338

HOME1
Homer protein homolog 1

1

1

High-throughput

0.536

High

1055346

CSN5
COP9 signalosome complex subunit 5

1

7

High-throughput

0.536

High

1055352

TRIM7
E3 ubiquitin-protein ligase TRIM7

1

1

High-throughput

0.536

High

1055369

MB212
Protein mab-21-like 2

1

1

High-throughput

0.536

High

657832

ELK4
ETS domain-containing protein Elk-4

2

5

High-throughput

0.521

High

823396

PAXI
Paxillin

2

4

High-throughput

0.521

High

848544

CAV2
Caveolin-2

2

7

High-throughput

0.521

High

974820

CAV1
Caveolin-1

2

7

High-throughput

0.521

High

1055340

ABI1
Abl interactor 1

2

3

High-throughput

0.521

High

1055342

SH2D3
SH2 domain-containing protein 3C

2

15

High-throughput

0.521

High

229950

NUAK1
NUAK family SNF1-like kinase 1

1

5

High-throughput

0.515

High

260559

TP4A3
Protein tyrosine phosphatase type IVA 3

1

2

High-throughput

0.515

High

1055336

Q7KZS0
SUMO-conjugating enzyme UBC9

1

5

High-throughput

0.515

High

416622

S10A6
Protein S100-A6

1

0

High-throughput

0.513

High

1055367

RPGF2
Rap guanine nucleotide exchange factor 2

1

0

High-throughput

0.513

High

1055357

PKHF2
Pleckstrin homology domain-containing family F member 2

1

1

High-throughput

0.494

High

269732

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

0

High-throughput

0.493

High

313277

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.493

High

941756

SERB
Phosphoserine phosphatase

1

0

High-throughput

0.493

High

1033467

ILK
Integrin-linked protein kinase

1

0

High-throughput

0.493

High

166929

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

1

High-throughput

0.489

High

455439

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.489

High

883913

SYJ2B
Synaptojanin-2-binding protein

1

1

High-throughput

0.489

High

885687

NXPH1
Neurexophilin-1

1

1

High-throughput

0.489

High

1055343

ANR44
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

1

1

High-throughput

0.489

High

1055345

F174A
Membrane protein FAM174A

1

1

High-throughput

0.489

High

658941

MK01
Mitogen-activated protein kinase 1

1

5

High-throughput

0.481

High

930215

UBC9
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.481

High

162741

XPO1
Exportin-1

1

2

High-throughput

0.479

High

298515

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

502099

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.479

High

718856

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

779409

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

815246

TISD
mRNA decay activator protein ZFP36L2

1

3

High-throughput

0.479

High

908535

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

1055333

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

1055337

LYRIC
Protein LYRIC

1

1

Small-scale

0.479

High

1055351

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.479

High

1055353

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

1055355

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.479

High

1055359

BRD7
Bromodomain-containing protein 7

1

3

High-throughput

0.479

High

1055361

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1055363

TNIK
TRAF2 and NCK-interacting protein kinase

1

3

High-throughput

0.479

High

1055366

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

5

Small-scale

0.479

High

1055368

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.479

High

1055358

LFG4
Protein lifeguard 4

1

1

High-throughput

0.470

High

1055330

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1055347

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1055350

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

275420

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

1

High-throughput

0.445

High

331010

PAK4
Serine/threonine-protein kinase PAK 4

1

5

High-throughput

0.445

High

1055364

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.438

High

903227

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.437

High

1029418

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

1055328

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.437

High

1055332

EMC4
ER membrane protein complex subunit 4

1

3

High-throughput

0.437

High

1055334

ASB18
Ankyrin repeat and SOCS box protein 18

1

5

High-throughput

0.437

High

1055344

TIP
T-cell immunomodulatory protein

1

1

High-throughput

0.437

High

1055349

ASB9
Ankyrin repeat and SOCS box protein 9

1

6

High-throughput

0.437

High

1055356

SFR19
Splicing factor, arginine/serine-rich 19

1

1

High-throughput

0.437

High

1055360

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

2

High-throughput

0.437

High

1055362

FBW1B
F-box/WD repeat-containing protein 11

1

2

High-throughput

0.437

High

402001

JUN
Transcription factor Jun

1

4

High-throughput

0.407

High

1055339

DAAF8
Dynein axonemal assembly factor 8

2

0

High-throughput

0.328

High

1055348

MGN2
Protein mago nashi homolog 2

2

0

High-throughput

0.316

High

1055370

CAN7
Calpain-7

2

0

High-throughput

0.316

High

571130

EGLN
Endoglin

1

0

High-throughput

0.279

Low

1055354

SMG9
Nonsense-mediated mRNA decay factor SMG9

1

0

High-throughput

0.279

Low

1055365

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

0

High-throughput

0.279

Low

1055331

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1055335

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.249

Low

1055341

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024