HitPredict

Interactor 1: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Interactor 2: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20562859
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 117
+	Hs
		305935 XRCC5_HUMAN (1-732): 0: 755: 100.00		GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27
+	Hs
		525052 XRCC5_HUMAN (1-732): 0: 755: 100.00		MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14
+	Hs
		523637 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00
+	Hs
		305934 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27
+	Hs
		523996 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21
+	Hs
		523992 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14