HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: FES1 (P38260)
Hsp70 nucleotide exchange factor FES1 (Factor exchange for SSA1 protein 1)
Gene: FES1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.728

Property	Details
Experiments	31242183, 37968396, 22635919, 24671421, 19536198, 16429126
Identification Methods	pull down, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 290
+	Sc
		523748 HSP71_YEAST (1-639): 0: 968: 97.04		FES1_YEAST (1-290): 1.29e-112: 328: 100.00
+	Sc
		645726 HSP74_YEAST (1-639): 0: 960: 81.62		FES1_YEAST (1-290): 1.29e-112: 328: 100.00
+	Sp
		207176 HSP71_SCHPO (1-639): 0: 962: 78.42		FES1_SCHPO (1-237): 8.87e-52: 173: 29.63
+	Dm
		1012129 HSP70_DROME (3-639): 0: 931: 69.74		Q95RI2_DROME (1-247): 8.99e-59: 191: 20.40
+	Dm
		391839 HSP71_DROME (3-639): 0: 931: 69.74		Q95RI2_DROME (1-247): 8.99e-59: 191: 20.40
+	Hs
		761527 HS71L_HUMAN (2-639): 0: 956: 72.08		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		600949 HSP76_HUMAN (4-639): 0: 950: 70.58		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		538024 HSP7C_HUMAN (2-639): 0: 945: 74.34		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		516178 HS71A_HUMAN (2-639): 0: 937: 73.01		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		516215 HS71B_HUMAN (2-639): 0: 937: 73.01		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13
+	Hs
		931139 HSP72_HUMAN (2-639): 0: 930: 71.23		HPBP1_HUMAN (1-251): 1e-45: 159: 21.13