HitPredict

Interactor 1: GP1BB (P13224)
Platelet glycoprotein Ib beta chain (GP-Ib beta) (GPIb-beta) (GPIbB) (Antigen CD42b-beta) (CD antigen CD42c)
Gene: GP1BB

Interactor 2: CLC2D (Q9UHP7)
C-type lectin domain family 2 member D (Lectin-like NK cell receptor) (Lectin-like transcript 1) (LLT-1) (Osteoclast inhibitory lectin)
Gene: CLEC2D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004888 - transmembrane signaling receptor activity GO:0005886 - plasma membrane GO:0007166 - cell surface receptor signaling pathway
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 206 Hs			1 191
+	Hs
		1268547 PXDN_HUMAN (2-165): 3.11e-45: 162: 16.97		CLC4A_HUMAN (42-191): 3.17e-38: 133: 18.79
+	Hs
		1218780 AGRA3_HUMAN (3-178): 5.38e-43: 155: 17.51		CLC4A_HUMAN (42-191): 3.17e-38: 133: 18.79
+	Hs
		1218776 AGRA3_HUMAN (3-178): 5.38e-43: 155: 17.51		CLC2B_HUMAN (48-187): 3.95e-37: 127: 41.43
+	Hs
		526505 GP1BB_HUMAN (1-206): 3.83e-44: 147: 100.00		CL12B_HUMAN (67-191): 2.26e-37: 132: 27.94
+	Hs
		59798 LRC4B_HUMAN (2-126): 3.67e-16: 78.1: 16.28		KLRG2_HUMAN (33-186): 7.9e-44: 152: 28.93
+	Hs
		1100740 R4RL2_HUMAN (10-134): 1.3e-13: 70.4: 21.43		CL12B_HUMAN (67-191): 2.26e-37: 132: 27.94
+	Hs
		299599 LRIG2_HUMAN (7-89): 9.89e-11: 62.3: 19.05		CLC4E_HUMAN (12-186): 2.39e-41: 140: 22.77
+	Hs
		1166673 LRIG3_HUMAN (6-89): 1.95e-10: 61.6: 19.05		CLC4A_HUMAN (42-191): 3.17e-38: 133: 18.79
+	Hs
		299565 LRIG2_HUMAN (7-89): 9.89e-11: 62.3: 19.05		CL12B_HUMAN (67-191): 2.26e-37: 132: 27.94
+	Hs
		1100734 LRIG3_HUMAN (6-89): 1.95e-10: 61.6: 19.05		CL12B_HUMAN (67-191): 2.26e-37: 132: 27.94
+	Hs
		1166424 LRC4C_HUMAN (2-126): 2.61e-17: 81.2: 15.75		CLC4G_HUMAN (74-189): 1.5e-29: 112: 26.36
+	Hs
		296667 SLIT2_HUMAN (19-92): 2.52e-11: 64.2: 16.22		CLC4D_HUMAN (54-185): 8.78e-36: 126: 21.09
+	Hs
		1100785 LRIG1_HUMAN (2-89): 5.55e-09: 57.3: 13.33		CL12B_HUMAN (67-191): 2.26e-37: 132: 27.94
+	Hs
		644626 LRIG1_HUMAN (2-89): 5.55e-09: 57.3: 13.33		NKG2A_HUMAN (23-188): 8.34e-38: 132: 19.77
+	Hs
		299573 LRIG2_HUMAN (7-89): 9.89e-11: 62.3: 19.05		CLC4D_HUMAN (54-185): 8.78e-36: 126: 21.09
+	Hs
		1263883 LRIG1_HUMAN (2-89): 5.55e-09: 57.3: 13.33		CLC4D_HUMAN (54-185): 8.78e-36: 126: 21.09