Protein: DCXR
L-xylulose reductase (XR) (EC 1.1.1.10) (Carbonyl reductase II) (Dicarbonyl/L-xylulose reductase) (Kidney dicarbonyl reductase) (kiDCR) (Short chain dehydrogenase/reductase family 20C member 1) (Sperm surface protein P34H)

Gene: DCXR
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q7Z4W1

Gene Ontology (top 5):
GO:0004090 - carbonyl reductase (NADPH) activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0005881 - cytoplasmic microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1278839

DCXR
L-xylulose reductase

4

16

High-throughput

0.893

High

1278855

SPHK1
Sphingosine kinase 1

4

1

Small-scale

0.691

High

1278850

DEFI6
Differentially expressed in FDCP 6 homolog

3

1

High-throughput

0.667

High

1278853

GLRX2
Glutaredoxin-2, mitochondrial

2

3

High-throughput

0.606

High

1107868

SQSTM
Sequestosome-1

2

0

High-throughput

0.559

High

1066235

DMWD
Dystrophia myotonica WD repeat-containing protein

1

2

High-throughput

0.536

High

1278840

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

1278848

TRIM5
Tripartite motif-containing protein 5

1

3

High-throughput

0.536

High

49116

BLT3B
Bridge-like lipid transfer protein family member 3B

1

0

High-throughput

0.513

High

1278842

NEK7
Serine/threonine-protein kinase Nek7

1

0

High-throughput

0.513

High

1278854

ASB6
Ankyrin repeat and SOCS box protein 6

1

0

High-throughput

0.513

High

422444

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

242135

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

318816

RHBT1
Rho-related BTB domain-containing protein 1

1

1

High-throughput

0.479

High

965059

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.479

High

1162398

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

3

High-throughput

0.479

High

1278846

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

1278847

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

1278852

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

2

High-throughput

0.479

High

1278856

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1278859

TRAF6
TNF receptor-associated factor 6

1

3

High-throughput

0.479

High

1008665

CRADD
Death domain-containing protein CRADD

1

0

High-throughput

0.460

High

279817

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

537414

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

589032

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

695820

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

727868

DNJA1
DnaJ homolog subfamily A member 1

1

0

High-throughput

0.458

High

851938

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

959197

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

1013413

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.458

High

1155502

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1278845

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1278849

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.458

High

1278851

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1278857

XPO7
Exportin-7

1

0

High-throughput

0.458

High

1278858

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.458

High

142362

PEX7
Peroxisomal targeting signal 2 receptor

1

4

High-throughput

0.445

High

563991

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.445

High

1209328

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

1278841

S39AB
Zinc transporter ZIP11

1

3

High-throughput

0.445

High

1278844

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

1

High-throughput

0.445

High

353418

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

1254422

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

140329

SDCB1
Syntenin-1

1

0

High-throughput

0.426

High

255098

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.426

High

261207

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.426

High

430087

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

1104003

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.426

High

330221

VENTX
Homeobox protein VENTX

1

2

High-throughput

0.407

High

1278843

S39AD
Zinc transporter ZIP13

1

3

High-throughput

0.407

High

886993

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

66893

SPDE4
Speedy protein E4

1

0

High-throughput

0.279

Low

106184

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

768532

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025