HitPredict

Interactor 1: MYH6 (P13533)
Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha)
Gene: MYH6

Interactor 2: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1939 Hs			1 487
+	Hs
		528371 MYH6_HUMAN (1-1939): 0: 1172: 100.00		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Hs
		528359 MYH6_HUMAN (1-1939): 0: 1172: 100.00		KAPCB_HUMAN (14-319): 8.38e-123: 364: 25.63
+	Hs
		568568 MYH10_HUMAN (26-1928): 0: 1015: 40.10		KAPCA_HUMAN (14-319): 7.68e-123: 364: 26.90
+	Hs
		725152 MYH10_HUMAN (26-1928): 0: 1015: 40.10		PAK2_HUMAN (8-300): 1.44e-118: 359: 40.26
+	Hs
		1023138 MYH13_HUMAN (1035-1939): 7.94e-63: 240: 17.02		STK4_HUMAN (1-487): 7.89e-170: 489: 100.00
+	Hs
		522609 MYH7_HUMAN (725-1816): 1.63e-62: 239: 17.14		STK4_HUMAN (1-487): 7.89e-170: 489: 100.00
+	Hs
		1023144 MYH15_HUMAN (927-1939): 7.98e-60: 230: 16.70		STK4_HUMAN (1-487): 7.89e-170: 489: 100.00
+	Hs
		528408 MYH8_HUMAN (1014-1939): 3.73e-59: 228: 15.86		STK4_HUMAN (1-487): 7.89e-170: 489: 100.00
+	Hs
		1023137 MYH2_HUMAN (1067-1939): 8.69e-56: 217: 15.24		STK4_HUMAN (1-487): 7.89e-170: 489: 100.00
+	Hs
		522545 MYH1_HUMAN (1102-1939): 1.21e-51: 204: 16.43		STK4_HUMAN (1-487): 7.89e-170: 489: 100.00
+	Hs
		1027453 MYH13_HUMAN (1035-1939): 7.94e-63: 240: 17.02		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Hs
		522610 MYH7_HUMAN (725-1816): 1.63e-62: 239: 17.14		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Hs
		1027458 MYH15_HUMAN (927-1939): 7.98e-60: 230: 16.70		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Hs
		528409 MYH8_HUMAN (1014-1939): 3.73e-59: 228: 15.86		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Hs
		1027452 MYH2_HUMAN (1067-1939): 8.69e-56: 217: 15.24		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Hs
		522546 MYH1_HUMAN (1102-1939): 1.21e-51: 204: 16.43		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Hs
		610795 MYH2_HUMAN (1067-1939): 8.69e-56: 217: 15.24		KAPCB_HUMAN (14-319): 8.38e-123: 364: 25.63
+	Hs
		568567 MYH9_HUMAN (1074-1939): 5.95e-55: 214: 16.42		KAPCA_HUMAN (14-319): 7.68e-123: 364: 26.90
+	Hs
		522538 MYH1_HUMAN (1102-1939): 1.21e-51: 204: 16.43		KAPCB_HUMAN (14-319): 8.38e-123: 364: 25.63
+	Hs
		610802 MYH4_HUMAN (1264-1939): 3.3e-45: 182: 15.09		KAPCB_HUMAN (14-319): 8.38e-123: 364: 25.63