HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: GNA11 (P29992)
Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha)
Gene: GNA11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	17110338, 26618866
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 359
+	Hs
		391317 CFTR_HUMAN (1-1480): 0: 1031: 100.00		GNAI2_HUMAN (7-358): 4.41e-161: 456: 50.14
+	Hs
		444657 CFTR_HUMAN (1-1480): 0: 1031: 100.00		GNAI3_HUMAN (7-358): 1.15e-160: 455: 50.57
+	Hs
		528938 CFTR_HUMAN (1-1480): 0: 1031: 100.00		GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83
+	Hs
		528513 CFTR_HUMAN (1-1480): 0: 1031: 100.00		GNAZ_HUMAN (7-358): 3e-145: 416: 46.76