HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ADT1 (P12235)
ADP/ATP translocase 1 (ADP,ATP carrier protein 1) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (Adenine nucleotide translocator 1) (ANT 1) (Solute carrier family 25 member 4)
Gene: SLC25A4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	21958963, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 298
+	Hs
		528962 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ADT3_HUMAN (1-298): 1.75e-117: 341: 88.26
+	Hs
		424741 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ADT2_HUMAN (1-297): 7.84e-117: 339: 89.23
+	Rn
		620057 TAU_RAT (1-758): 3.21e-76: 263: 72.11		ADT1_RAT (1-298): 7.36e-120: 347: 95.64
+	Rn
		98747 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		ADT1_RAT (1-298): 7.36e-120: 347: 95.64
+	Rn
		620060 TAU_RAT (1-758): 3.21e-76: 263: 72.11		ADT2_RAT (1-297): 2.44e-117: 340: 90.24
+	Rn
		98750 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		ADT2_RAT (1-297): 2.44e-117: 340: 90.24
+	Mm
		530727 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		ADT1_MOUSE (1-298): 5.73e-120: 347: 95.30
+	Mm
		530731 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		ADT2_MOUSE (1-297): 1.21e-117: 341: 90.24
+	Hs
		530540 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		S2513_HUMAN (3-271): 1.96e-44: 161: 20.07
+	Hs
		552358 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		ADT3_HUMAN (1-298): 1.75e-117: 341: 88.26
+	Hs
		425000 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		ADT2_HUMAN (1-297): 7.84e-117: 339: 89.23
+	Hs
		292061 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		S2512_HUMAN (12-119): 1.12e-19: 91: 22.02
+	Mm
		530858 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		S2512_MOUSE (12-119): 5.34e-20: 91.8: 21.10