Interactor 1: AT1A3 (P13637)
Sodium/potassium-transporting ATPase subunit alpha-3 (Na(+)/K(+) ATPase alpha-3 subunit) (EC 7.2.2.13) (Na(+)/K(+) ATPase alpha(III) subunit) (Sodium pump subunit alpha-3)
Gene: ATP1A3

Interactor 2: AT1B3 (P54709)
Sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3) (ATPB-3) (CD antigen CD298)
Gene: ATP1B3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cation_ATPase_C~Na_K-ATPase
Common GO terms GO:0005886 - plasma membrane
GO:0005890 - sodium:potassium-exchanging ATPase complex
GO:0006883 - intracellular sodium ion homeostasis
GO:0030007 - intracellular potassium ion homeostasis
GO:0036376 - sodium ion export across plasma membrane
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1013
Hs

1 279
+ Hs
+ Hs
+ Hs
+ Ss
+ Mm
+ Hs
+ Oc
+ Gg
+ Hs
+ Hs
+ Hs
+ Oc
+ Ss
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024