HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26618866, 29924966
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0016887 - ATP hydrolysis activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 535
+	Hs
		529628 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		528768 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		528502 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		528759 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Dm
		1182042 Q7KTD0_DROME (788-1466): 6.87e-53: 206: 14.95		Q9VHL2_DROME (5-525): 0: 554: 31.75
+	Sc
		760727 YCFI_YEAST (748-1433): 4.8e-56: 216: 14.59		TCPG_YEAST (5-528): 0: 537: 28.33