HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: HSPA9 (P38646)
Stress-70 protein, mitochondrial (EC 3.6.4.10) (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005739 - mitochondrion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 679
+	Hs
		529203 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HS71L_HUMAN (49-673): 0: 883: 47.59
+	Hs
		528943 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HSP7C_HUMAN (51-653): 0: 882: 50.16
+	Hs
		529020 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HSP76_HUMAN (49-673): 0: 873: 48.68
+	Hs
		516148 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HS71A_HUMAN (51-652): 0: 872: 49.27
+	Hs
		529415 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HSP72_HUMAN (50-653): 0: 867: 49.11
+	Mm
		530769 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		HSP7C_MOUSE (51-653): 0: 882: 50.16
+	Mm
		530698 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		HS71L_MOUSE (49-673): 0: 877: 47.43
+	Rn
		620016 TAU_RAT (1-758): 3.21e-76: 263: 72.11		HSPA9_RAT (1-679): 0: 863: 98.38
+	Mm
		530828 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		HS71A_MOUSE (51-673): 0: 867: 47.75
+	Mm
		530699 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		HSP72_MOUSE (50-669): 0: 863: 48.35
+	Hs
		551608 NFH_HUMAN (113-708): 1.12e-25: 115: 10.96		HSP72_HUMAN (50-653): 0: 867: 49.11
+	Hs
		536553 MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24		HSP7C_HUMAN (51-653): 0: 882: 50.16
+	Hs
		537748 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		HSP7C_HUMAN (51-653): 0: 882: 50.16
+	Hs
		801478 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		HSPA9_HUMAN (1-679): 0: 873: 100.00
+	Hs
		528941 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		BIP_HUMAN (53-677): 0: 566: 50.55
+	Rn
		448090 TAU_RAT (1-758): 3.21e-76: 263: 72.11		BIP_RAT (53-677): 0: 567: 51.97
+	Rn
		98649 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		BIP_RAT (53-677): 0: 567: 51.97
+	Hs
		95997 E7EVA0_HUMAN (214-725): 3.71e-32: 137: 25.82		BIP_HUMAN (53-677): 0: 566: 50.55
+	Hs
		534676 MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24		BIP_HUMAN (53-677): 0: 566: 50.55
+	Hs
		535432 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		BIP_HUMAN (53-677): 0: 566: 50.55