HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: DNJC5 (Q9H3Z4)
DnaJ homolog subfamily C member 5 (Ceroid-lipofuscinosis neuronal protein 4) (Cysteine string protein) (CSP)
Gene: DNAJC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	12039948, 16857740
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 198
+	Hs
		529547 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJA3_HUMAN (6-117): 2.03e-42: 149: 31.93
+	Hs
		279273 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJB5_HUMAN (13-108): 7.56e-39: 137: 38.10
+	Hs
		528577 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJB2_HUMAN (15-117): 6.32e-39: 137: 35.25
+	Hs
		529849 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DJB11_HUMAN (12-95): 2.85e-37: 134: 44.05
+	Hs
		529482 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJB3_HUMAN (15-112): 3.68e-38: 130: 38.18
+	Hs
		257902 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJB6_HUMAN (17-79): 1.09e-20: 89.4: 60.94