Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: VTI1B (Q9UEU0)
Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1)
Gene: VTI1B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.55 0.601

The method score is based on:

Property Details
Experiments 35156780, 18570918
Identification Methods protein complementation assay, affinity chromatography technology, ubiquitin reconstruction, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005765 - lysosomal membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006904 - vesicle docking involved in exocytosis
GO:0019869 - chloride channel inhibitor activity
and 3 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024