Protein: MTAP2
Microtubule-associated protein 2 (MAP-2)

Gene: MTAP2, MAP2
Organism: Homo sapiens
Interactions: 72
UniProt ID: P11137

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0002162 - dystroglycan binding
GO:0005198 - structural molecule activity
GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

528942

TAU
Microtubule-associated protein tau

5

15

Small-scale

0.922

High

536318

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

4

7

High-throughput

0.691

High

536332

GRB2
Growth factor receptor-bound protein 2

3

20

Small-scale

0.686

High

536345

DGUOK
Deoxyguanosine kinase, mitochondrial

3

3

High-throughput

0.667

High

536358

ARMC1
Armadillo repeat-containing protein 1

3

1

High-throughput

0.667

High

536312

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

3

14

Small-scale

0.656

High

536307

MTAP2
Microtubule-associated protein 2

1

15

Small-scale

0.647

High

536350

TBA1A
Tubulin alpha-1A chain

3

20

Small-scale

0.646

High

536310

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

2

9

Small-scale

0.611

High

124214

HAX1
HCLS1-associated protein X-1

3

2

High-throughput

0.609

High

536360

NUFP1
FMR1-interacting protein NUFIP1

3

2

High-throughput

0.609

High

536334

MDM2
E3 ubiquitin-protein ligase Mdm2

2

2

Small-scale

0.595

High

536341

DCTN1
Dynactin subunit 1

2

20

High-throughput

0.584

High

440318

FYN
Tyrosine-protein kinase Fyn

2

14

Small-scale

0.571

High

536336

MYO7A
Unconventional myosin-VIIa

1

11

Small-scale

0.561

High

536340

DAG1
Dystroglycan 1

1

11

Small-scale

0.561

High

536314

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

14

High-throughput

0.536

High

536315

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

14

High-throughput

0.536

High

536326

GSK3A
Glycogen synthase kinase-3 alpha

1

20

High-throughput

0.536

High

536328

GPM6A
Neuronal membrane glycoprotein M6-a

1

7

High-throughput

0.536

High

536356

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

8

High-throughput

0.536

High

387368

APOE
Apolipoprotein E

1

2

High-throughput

0.515

High

536311

JUNB
Transcription factor JunB

1

10

High-throughput

0.512

High

421385

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

451109

NFL
Neurofilament light polypeptide

1

20

Small-scale

0.501

High

536308

ACTN1
Alpha-actinin-1

1

16

Small-scale

0.501

High

536309

SRC
Proto-oncogene tyrosine-protein kinase Src

1

14

Small-scale

0.501

High

536317

MARK3
MAP/microtubule affinity-regulating kinase 3

1

13

Small-scale

0.501

High

536330

ACTB
Actin, cytoplasmic 1

1

17

Small-scale

0.501

High

536342

PLEC
Plectin

1

20

Small-scale

0.501

High

536353

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

10

High-throughput

0.501

High

536354

MARK4
MAP/microtubule affinity-regulating kinase 4

1

13

Small-scale

0.501

High

536355

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

10

High-throughput

0.501

High

240581

PRKN
E3 ubiquitin-protein ligase parkin

1

13

Small-scale

0.479

High

271853

OBSL1
Obscurin-like protein 1

1

17

High-throughput

0.479

High

411252

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

536313

EGR1
Early growth response protein 1

1

4

High-throughput

0.479

High

536316

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

536319

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

536320

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

536321

MSX2
Homeobox protein MSX-2

1

9

High-throughput

0.479

High

536322

SYUA
Alpha-synuclein

1

6

High-throughput

0.479

High

536323

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

536324

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

10

High-throughput

0.479

High

536327

MECP2
Methyl-CpG-binding protein 2

1

10

High-throughput

0.479

High

536331

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

536333

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

536335

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

536338

TBB3
Tubulin beta-3 chain

1

16

Small-scale

0.479

High

536343

MARE1
Microtubule-associated protein RP/EB family member 1

1

11

High-throughput

0.479

High

536349

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

536351

FBXW8
F-box/WD repeat-containing protein 8

1

10

High-throughput

0.479

High

536357

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.479

High

536359

HECW2
E3 ubiquitin-protein ligase HECW2

1

10

High-throughput

0.479

High

536361

MARE3
Microtubule-associated protein RP/EB family member 3

1

11

High-throughput

0.479

High

536346

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

4

High-throughput

0.470

High

377378

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

516740

SCHI1
Schwannomin-interacting protein 1

1

0

High-throughput

0.458

High

536348

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

536352

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

213053

CP110
Centriolar coiled-coil protein of 110 kDa

1

2

Small-scale

0.457

High

536329

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.445

High

536344

NF2L2
Nuclear factor erythroid 2-related factor 2

1

6

High-throughput

0.445

High

536347

CP135
Centrosomal protein of 135 kDa

1

15

High-throughput

0.445

High

105196

APRIO
Alternative prion protein

1

7

High-throughput

0.437

High

405728

MYCN
N-myc proto-oncogene protein

1

16

High-throughput

0.437

High

261067

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.426

High

536325

YAP1
Transcriptional coactivator YAP1

1

16

High-throughput

0.408

High

344078

PTBP3
Polypyrimidine tract-binding protein 3

1

17

High-throughput

0.407

High

536339

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.249

Low

536337

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025