HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ATAD1 (Q8NBU5)
Outer mitochondrial transmembrane helix translocase (EC 7.4.2.-) (ATPase family AAA domain-containing protein 1) (hATAD1) (Thorase)
Gene: ATAD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36634849, 35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0007613 - memory
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 361
+	Hs
		282446 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		KTNA1_HUMAN (3-358): 6.9e-105: 318: 30.73
+	Hs
		529511 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PRS8_HUMAN (13-359): 1.75e-100: 304: 28.00
+	Hs
		529530 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PRS10_HUMAN (11-358): 9.85e-100: 302: 27.97
+	Hs
		529287 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PRS6B_HUMAN (8-338): 4.05e-97: 296: 26.65
+	Hs
		529426 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		TERA_HUMAN (77-356): 6.65e-91: 291: 33.67
+	Mm
		530794 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		TERA_MOUSE (77-356): 6.65e-91: 291: 33.67
+	Hs
		530059 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		KATL2_HUMAN (85-357): 1.16e-47: 171: 37.59
+	Rn
		580726 MTAP2_RAT (30-758): 6.27e-36: 149: 29.55		KTNA1_RAT (3-358): 2.47e-100: 307: 30.19
+	Hs
		536329 MTAP2_HUMAN (16-758): 7.48e-30: 129: 23.42		TERA_HUMAN (77-356): 6.65e-91: 291: 33.67
+	Hs
		551609 NFH_HUMAN (113-708): 1.12e-25: 115: 10.96		TERA_HUMAN (77-356): 6.65e-91: 291: 33.67
+	Mm
		631797 MTAP2_MOUSE (26-758): 2.26e-30: 131: 24.41		SPAST_MOUSE (88-346): 1.47e-52: 185: 40.39
+	Mm
		1455914 PCLO_MOUSE (31-654): 3.4e-09: 62.7: 10.40		SPAST_MOUSE (88-346): 1.47e-52: 185: 40.39