HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: DVL3 (Q92997)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36634849
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 716
+	Hs
		159310 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		DVL1_HUMAN (1-716): 1.2e-144: 440: 63.38
+	Hs
		159481 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		DVL2_HUMAN (3-716): 2.28e-126: 394: 64.82
+	Hs
		529719 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		DLG1_HUMAN (17-656): 2.84e-48: 185: 13.51
+	Hs
		529430 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		AFAD_HUMAN (130-681): 8.93e-46: 178: 15.16
+	Rn
		205642 TAU_RAT (1-758): 3.21e-76: 263: 72.11		AFAD_RAT (130-669): 2.07e-42: 168: 14.76
+	Rn
		98639 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		AFAD_RAT (130-669): 2.07e-42: 168: 14.76
+	Hs
		530246 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MAGI1_HUMAN (130-593): 3.84e-20: 98.1: 9.70
+	Mm
		619283 NFH_MOUSE (89-708): 1.88e-28: 124: 11.68		DLG4_MOUSE (96-628): 1.46e-52: 195: 14.34
+	Mm
		92771 D3Z656_MOUSE (129-637): 4.2e-11: 68.8: 11.79		DLG4_MOUSE (96-628): 1.46e-52: 195: 14.34
+	Mm
		1223655 SYNJ1_MOUSE (331-733): 9.63e-11: 67.7: 12.02		DLG4_MOUSE (96-628): 1.46e-52: 195: 14.34
+	Hs
		319055 K0754_HUMAN (410-757): 3.14e-12: 72.8: 8.33		AFAD_HUMAN (130-681): 8.93e-46: 178: 15.16
+	Mm
		1424398 PCLO_MOUSE (31-654): 3.4e-09: 62.7: 10.40		RIMS2_MOUSE (63-700): 6.07e-42: 167: 13.68
+	Ce
		109124 TTN1_CAEEL (4-632): 1.92e-10: 67.2: 11.92		DLG1_CAEEL (20-640): 3.11e-29: 126: 15.01