Protein: MS116
ATP-dependent RNA helicase MSS116, mitochondrial (EC 3.6.4.13)

Gene: MS116, MSS116
Organism: Saccharomyces cerevisiae S288C
Interactions: 156
UniProt ID: P15424

Gene Ontology (top 5):
GO:0000372 - Group I intron splicing
GO:0000373 - Group II intron splicing
GO:0000963 - mitochondrial RNA processing
GO:0002151 - G-quadruplex RNA binding
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

584229

CIC1
Proteasome-interacting protein CIC1

1

6

High-throughput

0.691

High

584177

XRN1
5'-3' exoribonuclease 1

3

7

Small-scale

0.640

High

584178

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

6

High-throughput

0.618

High

584189

SPB4
ATP-dependent rRNA helicase SPB4

1

18

High-throughput

0.618

High

584230

DHH1
ATP-dependent RNA helicase DHH1

1

17

High-throughput

0.618

High

584249

MRH4
ATP-dependent RNA helicase MRH4, mitochondrial

1

16

Small-scale

0.618

High

584270

DHR1
Probable ATP-dependent RNA helicase DHR1

1

13

High-throughput

0.618

High

584287

DBP10
ATP-dependent RNA helicase DBP10

1

18

High-throughput

0.618

High

554547

RM02
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.586

High

584213

RM03
Large ribosomal subunit protein mL44

1

0

High-throughput

0.586

High

584201

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

2

High-throughput

0.584

High

584282

RTC1
Restriction of telomere capping protein 1

1

15

High-throughput

0.578

High

584196

RL8B
Large ribosomal subunit protein eL8B

1

15

High-throughput

0.575

High

584200

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

15

High-throughput

0.553

High

584225

GBLP
Small ribosomal subunit protein RACK1

1

20

High-throughput

0.553

High

584243

RS12
Small ribosomal subunit protein eS12

1

6

High-throughput

0.553

High

561660

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

Small-scale

0.537

High

584254

BRE5
UBP3-associated protein BRE5

1

10

High-throughput

0.536

High

584258

NOP13
Nucleolar protein 13

1

10

High-throughput

0.536

High

584276

ESF1
Pre-rRNA-processing protein ESF1

1

4

High-throughput

0.536

High

584281

NOP6
Nucleolar protein 6

1

2

High-throughput

0.536

High

584238

DSN1
Kinetochore-associated protein DSN1

2

6

High-throughput

0.533

High

584180

SIS1
Protein SIS1

2

8

High-throughput

0.521

High

584208

RSSA1
Small ribosomal subunit protein uS2A

2

12

High-throughput

0.521

High

584175

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.513

High

584233

SERA
D-3-phosphoglycerate dehydrogenase 1

1

4

High-throughput

0.494

High

584193

MIG1
Regulatory protein MIG1

1

7

High-throughput

0.489

High

403336

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

10

Small-scale

0.479

High

409904

RL25
Large ribosomal subunit protein uL23

1

8

High-throughput

0.479

High

430766

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

3

Small-scale

0.479

High

433411

RL26A
Large ribosomal subunit protein uL24A

1

10

High-throughput

0.479

High

434781

RS3
Small ribosomal subunit protein uS3

1

7

High-throughput

0.479

High

438604

SC160
Protein SCP160

1

16

High-throughput

0.479

High

441672

RS14A
Small ribosomal subunit protein uS11A

1

8

High-throughput

0.479

High

453103

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

1

Small-scale

0.479

High

454839

RS19A
Small ribosomal subunit protein eS19A

1

10

High-throughput

0.479

High

510150

HSP77
Import motor subunit, mitochondrial

1

10

High-throughput

0.479

High

514423

RS18A
Small ribosomal subunit protein uS13A

1

6

High-throughput

0.479

High

517872

SSBP1
Single-stranded nucleic acid-binding protein

1

10

High-throughput

0.479

High

578763

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.479

High

584182

RRP43
Exosome complex component RRP43

1

4

High-throughput

0.479

High

584185

KRR1
KRR1 small subunit processome component

1

9

High-throughput

0.479

High

584188

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

2

High-throughput

0.479

High

584197

RM09
Large ribosomal subunit protein uL3m

1

8

High-throughput

0.479

High

584203

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

18

High-throughput

0.479

High

584207

RM06
Large ribosomal subunit protein uL6m

1

2

High-throughput

0.479

High

584209

HSP78
Heat shock protein 78, mitochondrial

1

7

High-throughput

0.479

High

584211

RM38
Large ribosomal subunit protein uL14m

1

1

High-throughput

0.479

High

584212

RS27A
Small ribosomal subunit protein eS27A

1

6

High-throughput

0.479

High

584214

RM07
Large ribosomal subunit protein uL5m

1

5

High-throughput

0.479

High

584228

RS20
Small ribosomal subunit protein uS10

1

9

High-throughput

0.479

High

584240

UTP10
U3 small nucleolar RNA-associated protein 10

1

6

High-throughput

0.479

High

584242

LSM1
LSM1-LSM7 complex subunit LSM1

1

5

High-throughput

0.479

High

584246

RL4P
Large ribosomal subunit protein uL4m

1

2

High-throughput

0.479

High

584247

RMD9
RNA-binding protein RMD9, mitochondrial

1

1

High-throughput

0.479

High

584250

EIF2A
Eukaryotic translation initiation factor 2A

1

5

High-throughput

0.479

High

584251

PESC
Pescadillo homolog

1

8

High-throughput

0.479

High

584255

GIS2
Zinc finger protein GIS2

1

8

High-throughput

0.479

High

584257

RM22
Large ribosomal subunit protein uL22m

1

3

High-throughput

0.479

High

584259

ORC1
Origin recognition complex subunit 1

1

6

High-throughput

0.479

High

584261

RS15
Small ribosomal subunit protein uS19

1

7

High-throughput

0.479

High

584265

XRN2
5'-3' exoribonuclease 2

1

7

High-throughput

0.479

High

584268

RT17
Small ribosomal subunit protein uS17m

1

3

High-throughput

0.479

High

584269

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.479

High

584284

RS10A
Small ribosomal subunit protein eS10A

1

9

High-throughput

0.479

High

584285

TMA46
Translation machinery-associated protein 46

1

2

High-throughput

0.479

High

584286

YRA1
RNA annealing protein YRA1

1

13

High-throughput

0.479

High

584288

RM23
Large ribosomal subunit protein uL13m

1

9

High-throughput

0.479

High

382819

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

397518

CBP2
Cytochrome B pre-mRNA-processing protein 2

1

0

High-throughput

0.458

High

477503

MYO1
Myosin-1

1

0

Small-scale

0.458

High

569457

RM31
Large ribosomal subunit protein mL60

1

0

High-throughput

0.458

High

584176

RM33
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.458

High

584179

RM20
Large ribosomal subunit protein mL58

1

0

High-throughput

0.458

High

584181

RM32
Large ribosomal subunit protein bL32m

1

0

High-throughput

0.458

High

584186

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.458

High

584187

IMG2
Large ribosomal subunit protein mL49

1

0

High-throughput

0.458

High

584199

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.458

High

584202

PT309
Mitochondrial COX1 translation regulator PET309

1

0

Small-scale

0.458

High

584205

PT127
Putative mitochondrial translation system component PET127

1

0

High-throughput

0.458

High

584206

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

584215

RM10
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.458

High

584216

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.458

High

584217

RM24
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.458

High

584218

RM27
Large ribosomal subunit protein mL41

1

0

High-throughput

0.458

High

584219

RM28
Large ribosomal subunit protein mL40

1

0

High-throughput

0.458

High

584220

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.458

High

584221

RM36
Large ribosomal subunit protein bL31m

1

0

High-throughput

0.458

High

584222

RM37
Large ribosomal subunit protein mL54

1

0

High-throughput

0.458

High

584223

RM39
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.458

High

584224

RM40
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.458

High

584232

MRX1
MIOREX complex component 1

1

0

High-throughput

0.458

High

584235

LSM5
LSM complex subunit LSM5

1

0

High-throughput

0.458

High

584236

RRG9
Required for respiratory growth protein 9, mitochondrial

1

0

High-throughput

0.458

High

584239

RN49
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.458

High

584248

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.458

High

584253

RM50
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.458

High

584263

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.458

High

584267

ATP25
ATPase synthesis protein 25, mitochondrial

1

0

High-throughput

0.458

High

584271

RM34
Large ribosomal subunit protein bL34m

1

0

High-throughput

0.458

High

584273

RM51
Large ribosomal subunit protein mL43

1

0

High-throughput

0.458

High

584274

RRG8
Required for respiratory growth protein 8, mitochondrial

1

0

High-throughput

0.458

High

584277

MHR1
Large ribosomal subunit protein mL67

1

0

High-throughput

0.458

High

584279

RM35
Large ribosomal subunit protein mL38

1

0

High-throughput

0.458

High

584262

UBC7
Ubiquitin-conjugating enzyme E2 7

1

3

High-throughput

0.457

High

367880

ENO2
Enolase 2

1

3

High-throughput

0.445

High

392153

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.445

High

394186

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

432476

RL7A
Large ribosomal subunit protein uL30A

1

12

High-throughput

0.445

High

434317

RL15A
Large ribosomal subunit protein eL15A

1

3

High-throughput

0.445

High

511729

RS24A
Small ribosomal subunit protein eS24A

1

5

High-throughput

0.445

High

522939

HSP71
Heat shock protein SSA1

1

16

High-throughput

0.445

High

525826

HSP72
Heat shock protein SSA2

1

16

High-throughput

0.445

High

569894

RL3
Large ribosomal subunit protein uL3

1

6

High-throughput

0.445

High

584184

GBP2
Serine/arginine

1

8

High-throughput

0.445

High

584191

RS5
Small ribosomal subunit protein uS7

1

2

High-throughput

0.445

High

584198

HS104
Heat shock protein 104

1

6

High-throughput

0.445

High

584204

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

584244

RL4B
Large ribosomal subunit protein uL4B

1

9

High-throughput

0.445

High

584245

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

2

High-throughput

0.445

High

584264

RL6A
Large ribosomal subunit protein eL6A

1

6

High-throughput

0.445

High

584272

RRP5
rRNA biogenesis protein RRP5

1

12

High-throughput

0.445

High

149553

RS9A
Small ribosomal subunit protein uS4A

1

9

High-throughput

0.437

High

380946

H2B1
Histone H2B.1

1

6

High-throughput

0.437

High

381384

H2B2
Histone H2B.2

1

6

High-throughput

0.437

High

383486

RS17A
Small ribosomal subunit protein eS17A

1

8

High-throughput

0.437

High

419578

H2A2
Histone H2A.2

1

6

High-throughput

0.437

High

435737

RS13
Small ribosomal subunit protein uS15

1

7

High-throughput

0.437

High

502813

RS22A
Small ribosomal subunit protein uS8A

1

8

High-throughput

0.437

High

504009

RL31A
Large ribosomal subunit protein eL31A

1

13

High-throughput

0.437

High

512225

RS6A
Small ribosomal subunit protein eS6A

1

10

High-throughput

0.437

High

512783

RS8A
Small ribosomal subunit protein eS8A

1

8

High-throughput

0.437

High

558553

CAF20
Cap-associated protein CAF20

1

4

High-throughput

0.437

High

584183

RS2
Small ribosomal subunit protein uS5

1

10

High-throughput

0.437

High

584192

RS7A
Small ribosomal subunit protein eS7A

1

6

High-throughput

0.437

High

584194

TF2B
Transcription initiation factor IIB

1

8

High-throughput

0.437

High

584195

BMH1
Protein BMH1

1

10

High-throughput

0.437

High

584210

RS3A1
Small ribosomal subunit protein eS1A

1

8

High-throughput

0.437

High

584227

NU170
Nucleoporin NUP170

1

3

High-throughput

0.437

High

584231

LAA1
AP-1 accessory protein LAA1

1

7

High-throughput

0.437

High

584234

LSM4
LSM complex subunit LSM4

1

1

High-throughput

0.437

High

584237

ULP2
Ubiquitin-like-specific protease 2

1

5

High-throughput

0.437

High

584260

H3
Histone H3

1

19

High-throughput

0.437

High

584266

LGE1
Transcriptional regulatory protein LGE1

1

3

High-throughput

0.437

High

584275

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

4

High-throughput

0.437

High

584280

VAM6
Vacuolar morphogenesis protein 6

1

6

High-throughput

0.437

High

584283

SGO1
Shugoshin

1

6

High-throughput

0.437

High

359136

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

427120

RLA0
Large ribosomal subunit protein uL10

1

7

High-throughput

0.407

High

570204

RS17B
Small ribosomal subunit protein eS17B

1

8

High-throughput

0.407

High

584190

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.407

High

584241

RL17B
Large ribosomal subunit protein uL22B

1

7

High-throughput

0.407

High

584278

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

4

High-throughput

0.407

High

584256

ELOA1
Elongin-A

1

0

High-throughput

0.279

Low

584252

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.249

Low

584226

SEA4
SEH-associated protein 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025