HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: DNJB9 (Q9UBS3)
DnaJ homolog subfamily B member 9 (Endoplasmic reticulum DNA J domain-containing protein 4) (ER-resident protein ERdj4) (ERdj4) (Microvascular endothelial differentiation gene 1 protein) (Mdg-1)
Gene: DNAJB9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~Thioredoxin
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0034976 - response to endoplasmic reticulum stress
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 645 Hs			1 223
+	Hs
		531914 PDIA4_HUMAN (1-645): 0: 571: 100.00		DJB14_HUMAN (10-174): 1.47e-46: 159: 31.74
+	Hs
		532011 PDIA4_HUMAN (1-645): 0: 571: 100.00		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Hs
		532000 PDIA4_HUMAN (1-645): 0: 571: 100.00		DJB12_HUMAN (2-177): 4.03e-44: 153: 29.28
+	Hs
		532027 PDIA4_HUMAN (1-645): 0: 571: 100.00		DJC16_HUMAN (10-135): 4.26e-41: 150: 36.15
+	Hs
		531897 PDIA4_HUMAN (1-645): 0: 571: 100.00		DJC10_HUMAN (6-219): 3.47e-40: 148: 25.33
+	Hs
		532013 PDIA4_HUMAN (1-645): 0: 571: 100.00		DNJ5B_HUMAN (19-203): 1.4e-43: 146: 27.27
+	Rn
		956846 DJC10_RAT (45-279): 6.21e-44: 170: 22.67		DNJB9_RAT (1-223): 5.29e-70: 215: 92.38
+	Hs
		423379 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		DNJB9_HUMAN (1-223): 5.42e-72: 220: 100.00
+	Hs
		1067845 PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51		DNJB9_HUMAN (1-223): 5.42e-72: 220: 100.00
+	Hs
		1220492 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Rn
		1115513 DJC10_RAT (45-279): 6.21e-44: 170: 22.67		DJB11_RAT (4-104): 3.43e-40: 142: 41.18
+	Hs
		423304 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		DJB14_HUMAN (10-174): 1.47e-46: 159: 31.74
+	Hs
		423380 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Hs
		423372 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		DJB12_HUMAN (2-177): 4.03e-44: 153: 29.28
+	Hs
		1067846 PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Hs
		423398 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		DJC16_HUMAN (10-135): 4.26e-41: 150: 36.15
+	Hs
		636249 PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35		DNJB1_HUMAN (24-212): 4.11e-48: 162: 28.14
+	Hs
		1067840 PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51		DJB12_HUMAN (2-177): 4.03e-44: 153: 29.28
+	Hs
		423286 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		DJC10_HUMAN (6-219): 3.47e-40: 148: 25.33
+	Hs
		1067759 PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51		DJC10_HUMAN (6-219): 3.47e-40: 148: 25.33