Protein: EAF2
ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein)

Gene: EAF2
Organism: Homo sapiens
Interactions: 35
UniProt ID: Q96CJ1

Gene Ontology (top 5):
GO:0003711 - transcription elongation factor activity
GO:0005654 - nucleoplasm
GO:0006368 - transcription elongation by RNA polymerase II
GO:0006915 - apoptotic process
GO:0008023 - transcription elongation factor complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1385964

ELL3
RNA polymerase II elongation factor ELL3

4

5

High-throughput

0.892

High

936612

ELL
RNA polymerase II elongation factor ELL

4

5

Small-scale

0.878

High

137341

ELL2
RNA polymerase II elongation factor ELL2

2

5

Small-scale

0.789

High

1385966

AFF4
AF4/FMR2 family member 4

4

3

High-throughput

0.699

High

1385962

EAF1
ELL-associated factor 1

3

0

High-throughput

0.638

High

960516

PSME3
Proteasome activator complex subunit 3

2

1

High-throughput

0.632

High

871995

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

4

High-throughput

0.628

High

1330673

BEND7
BEN domain-containing protein 7

3

1

High-throughput

0.625

High

1150153

TCEA2
Transcription elongation factor A protein 2

2

4

High-throughput

0.606

High

1161355

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

Small-scale

0.564

High

1385963

STAC3
SH3 and cysteine-rich domain-containing protein 3

1

2

High-throughput

0.560

High

1107451

BIRC2
Baculoviral IAP repeat-containing protein 2

1

0

High-throughput

0.549

High

822807

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.537

High

414381

P53
Cellular tumor antigen p53

1

0

High-throughput

0.536

High

1372023

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.536

High

1385965

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.536

High

336017

MED26
Mediator of RNA polymerase II transcription subunit 26

1

1

High-throughput

0.536

High

503637

TFPT
TCF3 fusion partner

1

1

Small-scale

0.529

High

1061810

TLE5
TLE family member 5

1

1

High-throughput

0.512

High

1063504

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.512

High

173194

XPO1
Exportin-1

1

2

High-throughput

0.479

High

1066435

RBBP4
Histone-binding protein RBBP4

1

1

Small-scale

0.479

High

1158954

RBBP7
Histone-binding protein RBBP7

1

1

Small-scale

0.479

High

1323124

CCAR2
Cell cycle and apoptosis regulator protein 2

1

1

Small-scale

0.479

High

159790

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

211587

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

0

Small-scale

0.458

High

576252

PO2F1
POU domain, class 2, transcription factor 1

1

0

Small-scale

0.458

High

783367

TRI23
E3 ubiquitin-protein ligase TRIM23

1

0

High-throughput

0.299

High

1279958

NECA2
N-terminal EF-hand calcium-binding protein 2

1

0

High-throughput

0.292

High

1314597

IHO1
Interactor of HORMAD1 protein 1

1

0

High-throughput

0.292

High

1325746

LNX2
Ligand of Numb protein X 2

1

0

High-throughput

0.292

High

1336430

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.292

High

1331833

SYT2
Synaptotagmin-2

1

0

High-throughput

0.279

Low

331591

KIF4A
Chromosome-associated kinesin KIF4A

1

0

High-throughput

0.269

Low

1385967

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025