HitPredict

Interactor 1: MSI1 (P13712)
Chromatin assembly factor 1 subunit p50 (CAF-1 p50 subunit) (IRA1 multicopy suppressor) (Protein MSI1)
Gene: MSI1

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	16015338, 22199229, 23034810
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 422 Sc			1 136
+	Sc
		765955 HAT2_YEAST (11-418): 3.73e-76: 244: 22.72		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Sc
		532818 MSI1_YEAST (1-422): 4.17e-86: 270: 100.00		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Hs
		903117 WDR5_HUMAN (160-422): 4.12e-59: 197: 15.91		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		903128 WDR5_HUMAN (160-422): 4.12e-59: 197: 15.91		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		903260 WDR5_HUMAN (160-422): 4.12e-59: 197: 15.91		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Sc
		730808 HAT2_YEAST (11-418): 3.73e-76: 244: 22.72		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Hs
		792992 LIS1_HUMAN (3-282): 1.64e-49: 174: 7.62		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Hs
		267767 TAF5L_HUMAN (35-270): 1.66e-30: 125: 10.94		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Dm
		356079 CAF1_DROME (11-252): 2.89e-31: 125: 10.28		H3_DROME (1-136): 6.6e-61: 185: 88.97
+	Hs
		934809 RBBP7_HUMAN (11-249): 7.85e-30: 121: 9.56		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Mm
		935449 Q3UJI2_MOUSE (11-249): 1.58e-29: 120: 9.56		H31_MOUSE (1-136): 3.24e-62: 188: 88.97
+	Hs
		952365 RBBP7_HUMAN (11-249): 7.85e-30: 121: 9.56		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		1083261 RBBP7_HUMAN (11-249): 7.85e-30: 121: 9.56		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Mm
		952742 Q3UJI2_MOUSE (11-249): 1.58e-29: 120: 9.56		H33_MOUSE (1-136): 1.25e-61: 187: 90.44
+	Hs
		1083292 RBBP7_HUMAN (11-249): 7.85e-30: 121: 9.56		H32_HUMAN (1-136): 6.6e-61: 185: 88.97
+	Hs
		934971 DAW1_HUMAN (288-422): 8.85e-29: 118: 16.91		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Mm
		952255 Q3UJI2_MOUSE (11-249): 1.58e-29: 120: 9.56		H32_MOUSE (1-136): 6.6e-61: 185: 88.97
+	Mm
		935452 RBBP4_MOUSE (11-233): 8.38e-28: 115: 9.40		H31_MOUSE (1-136): 3.24e-62: 188: 88.97
+	Mm
		952258 RBBP4_MOUSE (11-233): 8.38e-28: 115: 9.40		H32_MOUSE (1-136): 6.6e-61: 185: 88.97
+	Hs
		828241 RBBP7_HUMAN (11-249): 7.85e-30: 121: 9.56		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73