HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: LAMC3 (Q9Y6N6)
Laminin subunit gamma-3 (Laminin-12 subunit gamma) (Laminin-14 subunit gamma) (Laminin-15 subunit gamma)
Gene: LAMC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 1575
+	Hs
		877442 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		LAMB2_HUMAN (583-1575): 3.06e-72: 269: 21.37
+	Hs
		433157 COL12_HUMAN (90-221): 3.82e-40: 147: 23.36		LAMB1_HUMAN (246-1552): 4.93e-84: 307: 18.68
+	Hs
		532920 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMB2_HUMAN (583-1575): 3.06e-72: 269: 21.37
+	Hs
		502807 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMC1_HUMAN (775-1575): 6.36e-46: 184: 15.67
+	Hs
		533105 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		NOTC3_HUMAN (264-655): 1.76e-25: 117: 11.21
+	Hs
		532950 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMB3_HUMAN (327-627): 4.15e-22: 106: 19.76
+	Hs
		1045112 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		LAMB3_HUMAN (327-627): 4.15e-22: 106: 19.76
+	Hs
		172697 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		LAMA5_HUMAN (912-1122): 1.05e-12: 75.7: 19.01
+	Hs
		172640 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMA5_HUMAN (912-1122): 1.05e-12: 75.7: 19.01
+	Hs
		532951 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMC2_HUMAN (400-668): 4.41e-10: 66.9: 13.97
+	Hs
		532926 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		PGBM_HUMAN (561-708): 7.52e-09: 63: 19.46