Protein: DUS19
Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase TS-DSP1) (Low molecular weight dual specificity phosphatase 3) (LMW-DSP3) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1) (SAPK pathway-regulating phosphatase 1)

Gene: DUS19, DUSP19
Organism: Homo sapiens
Interactions: 95
UniProt ID: Q8WTR2

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0004860 - protein kinase inhibitor activity
GO:0005078 - MAP-kinase scaffold activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

162018

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

2

9

Small-scale

0.768

High

439798

INSR
Insulin receptor

1

20

High-throughput

0.698

High

952982

ACTB
Actin, cytoplasmic 1

4

13

High-throughput

0.692

High

560892

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

7

3

High-throughput

0.686

High

977774

ACTA
Actin, aortic smooth muscle

3

12

High-throughput

0.667

High

1257795

ACD11
Acyl-CoA dehydrogenase family member 11

3

2

High-throughput

0.667

High

853834

MK09
Mitogen-activated protein kinase 9

1

20

Small-scale

0.647

High

227116

SYNC
Asparagine--tRNA ligase, cytoplasmic

3

0

High-throughput

0.638

High

1201006

ACTBL
Beta-actin-like protein 2

2

12

High-throughput

0.628

High

181806

EPHB6
Ephrin type-B receptor 6

1

20

High-throughput

0.625

High

710392

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.625

High

703659

MK01
Mitogen-activated protein kinase 1

1

20

High-throughput

0.618

High

1355894

DUS19
Dual specificity protein phosphatase 19

1

19

High-throughput

0.618

High

1355899

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

6

Small-scale

0.618

High

1355906

STK26
Serine/threonine-protein kinase 26

1

4

High-throughput

0.618

High

1355908

NRBP
Nuclear receptor-binding protein

1

3

High-throughput

0.618

High

157656

CTRO
Citron Rho-interacting kinase

1

6

High-throughput

0.553

High

1355897

AURKB
Aurora kinase B

1

4

High-throughput

0.553

High

363615

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.541

High

410961

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.541

High

465585

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.541

High

641633

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.541

High

777727

VGFR3
Vascular endothelial growth factor receptor 3

1

20

High-throughput

0.541

High

778085

VGFR2
Vascular endothelial growth factor receptor 2

1

13

High-throughput

0.541

High

1034181

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

20

High-throughput

0.541

High

1034300

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.541

High

1145755

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.541

High

552847

TPR
Nucleoprotein TPR

1

9

High-throughput

0.536

High

717916

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

4

High-throughput

0.536

High

993264

ACTG
Actin, cytoplasmic 2

1

12

High-throughput

0.536

High

994310

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

4

High-throughput

0.536

High

1160699

DREB
Drebrin

1

4

High-throughput

0.536

High

1101760

PTK7
Inactive tyrosine-protein kinase 7

1

10

High-throughput

0.494

High

1310859

LMTK2
Serine/threonine-protein kinase LMTK2

1

20

High-throughput

0.494

High

1355910

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.494

High

991071

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

2

High-throughput

0.489

High

995449

TPM4
Tropomyosin alpha-4 chain

1

3

High-throughput

0.489

High

996505

ACTS
Actin, alpha skeletal muscle

1

9

High-throughput

0.489

High

1131689

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

1

High-throughput

0.489

High

1355909

COR1C
Coronin-1C

1

6

High-throughput

0.489

High

123413

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

2

High-throughput

0.479

High

532803

CH60
60 kDa heat shock protein, mitochondrial

1

5

High-throughput

0.479

High

584784

NDKA
Nucleoside diphosphate kinase A

1

6

High-throughput

0.479

High

606019

CAN2
Calpain-2 catalytic subunit

1

2

High-throughput

0.479

High

716447

PRDX5
Peroxiredoxin-5, mitochondrial

1

3

High-throughput

0.479

High

853494

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

6

High-throughput

0.479

High

881800

DHYS
Deoxyhypusine synthase

1

1

High-throughput

0.479

High

899150

TCPQ
T-complex protein 1 subunit theta

1

6

High-throughput

0.479

High

954978

S10AA
Protein S100-A10

1

1

High-throughput

0.479

High

982108

RAP1A
Ras-related protein Rap-1A

1

9

High-throughput

0.479

High

992622

IF5A1
Eukaryotic translation initiation factor 5A-1

1

5

High-throughput

0.479

High

1015074

ARF5
ADP-ribosylation factor 5

1

10

High-throughput

0.479

High

1110667

DCTN2
Dynactin subunit 2

1

2

High-throughput

0.479

High

1143933

2A5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

1

1

High-throughput

0.479

High

1147492

RHEB
GTP-binding protein Rheb

1

7

High-throughput

0.479

High

1212809

UBR4
E3 ubiquitin-protein ligase UBR4

1

5

High-throughput

0.479

High

1278773

HDGR2
Hepatoma-derived growth factor-related protein 2

1

1

High-throughput

0.479

High

1339421

NUD10
Diphosphoinositol polyphosphate phosphohydrolase 3-alpha

1

2

High-throughput

0.479

High

1355898

PARK7
Parkinson disease protein 7

1

7

High-throughput

0.479

High

1355900

TCPH
T-complex protein 1 subunit eta

1

3

High-throughput

0.479

High

1355902

PFD4
Prefoldin subunit 4

1

1

High-throughput

0.479

High

1355903

ARL8B
ADP-ribosylation factor-like protein 8B

1

13

High-throughput

0.479

High

124948

GTPB1
GTP-binding protein 1

1

2

High-throughput

0.470

High

1132525

NAA30
N-alpha-acetyltransferase 30

1

0

High-throughput

0.458

High

1219655

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.458

High

1333038

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

1

0

High-throughput

0.458

High

257560

TI17B
Mitochondrial import inner membrane translocase subunit Tim17-B

1

5

High-throughput

0.437

High

412971

CPNS1
Calpain small subunit 1

1

5

High-throughput

0.437

High

560029

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

3

High-throughput

0.437

High

624568

SPEE
Spermidine synthase

1

6

High-throughput

0.437

High

755758

MCM4
DNA replication licensing factor MCM4

1

7

High-throughput

0.437

High

857146

NSF
Vesicle-fusing ATPase

1

5

High-throughput

0.437

High

899499

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.437

High

902212

RAB13
Ras-related protein Rab-13

1

2

High-throughput

0.437

High

916185

BIEA
Biliverdin reductase A

1

1

High-throughput

0.437

High

1128243

MCM6
DNA replication licensing factor MCM6

1

7

High-throughput

0.437

High

1131335

GANAB
Neutral alpha-glucosidase AB

1

4

High-throughput

0.437

High

1135451

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

1

3

High-throughput

0.437

High

1145634

RCN1
Reticulocalbin-1

1

5

High-throughput

0.437

High

1278390

HDDC2
5'-deoxynucleotidase HDDC2

1

3

High-throughput

0.437

High

1355895

TCPW
T-complex protein 1 subunit zeta-2

1

4

High-throughput

0.437

High

1355896

AP3S1
AP-3 complex subunit sigma-1

1

8

High-throughput

0.437

High

1355901

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

2

High-throughput

0.437

High

1355904

CUED1
CUE domain-containing protein 1

1

1

High-throughput

0.437

High

1355905

TMOD3
Tropomodulin-3

1

5

High-throughput

0.437

High

1355907

MTFP1
Mitochondrial fission process protein 1

1

1

High-throughput

0.437

High

1355911

HIG1A
HIG1 domain family member 1A, mitochondrial

1

1

High-throughput

0.437

High

814550

FEN1
Flap endonuclease 1

3

0

High-throughput

0.347

High

654660

TCEA1
Transcription elongation factor A protein 1

2

0

High-throughput

0.318

High

49460

TM223
Transmembrane protein 223

1

0

High-throughput

0.249

Low

553250

KCRB
Creatine kinase B-type

1

0

High-throughput

0.249

Low

634143

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.249

Low

939811

ATPK
ATP synthase F(0) complex subunit f, mitochondrial

1

0

High-throughput

0.249

Low

1293625

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025