HitPredict

Interactor 1: CCL4 (P14097)
C-C motif chemokine 4 (Immune activation protein 2) (ACT-2) (ACT2) (Macrophage inflammatory protein 1-beta) (MIP-1-beta) (Protein H400) (SIS-gamma) (Small-inducible cytokine A4)
Gene: CCL4

Interactor 2: CCR1 (P51675)
C-C chemokine receptor type 1 (C-C CKR-1) (CC-CKR-1) (CCR-1) (CCR1) (Macrophage inflammatory protein 1-alpha receptor) (MIP-1alpha-R) (RANTES-R) (CD antigen CD191)
Gene: CCR1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9139699
Identification Methods	competition binding
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006954 - inflammatory response GO:0030595 - leukocyte chemotaxis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 92 Mm			1 355
+	Hs
		561728 CL3L1_HUMAN (1-92): 8e-38: 123: 59.78		CCR1_HUMAN (1-355): 1.1e-88: 272: 80.00
+	Hs
		526560 CCL4_HUMAN (1-92): 1.69e-37: 122: 76.09		CCR1_HUMAN (1-355): 1.1e-88: 272: 80.00
+	Hs
		686667 CCL14_HUMAN (1-92): 1.14e-35: 118: 45.16		CCR1_HUMAN (1-355): 1.1e-88: 272: 80.00
+	Mm
		500591 CCL3_MOUSE (1-92): 1.06e-36: 120: 59.78		CCR3_MOUSE (13-355): 3.59e-87: 268: 62.68
+	Mm
		500590 CCL3_MOUSE (1-92): 1.06e-36: 120: 59.78		CCR1_MOUSE (1-355): 4.62e-85: 263: 100.00
+	Hs
		1305163 CCL13_HUMAN (1-91): 2.11e-37: 122: 39.56		ACKR4_HUMAN (6-343): 1.47e-81: 254: 30.81
+	Hs
		783833 CCL13_HUMAN (1-91): 2.11e-37: 122: 39.56		CCR2_HUMAN (8-344): 1.3e-75: 239: 49.41
+	Hs
		561732 CL3L1_HUMAN (1-92): 8e-38: 123: 59.78		CCR3_HUMAN (1-355): 3.49e-72: 230: 58.03
+	Hs
		526564 CCL4_HUMAN (1-92): 1.69e-37: 122: 76.09		CCR3_HUMAN (1-355): 3.49e-72: 230: 58.03
+	Hs
		561733 CL3L1_HUMAN (1-92): 8e-38: 123: 59.78		CCR5_HUMAN (6-355): 3.76e-72: 229: 54.55
+	Hs
		849619 CCL13_HUMAN (1-91): 2.11e-37: 122: 39.56		CCR3_HUMAN (1-355): 3.49e-72: 230: 58.03
+	Hs
		526565 CCL4_HUMAN (1-92): 1.69e-37: 122: 76.09		CCR5_HUMAN (6-355): 3.76e-72: 229: 54.55
+	Hs
		849654 CCL13_HUMAN (1-91): 2.11e-37: 122: 39.56		CCR5_HUMAN (6-355): 3.76e-72: 229: 54.55
+	Hs
		849616 CCL14_HUMAN (1-92): 1.14e-35: 118: 45.16		CCR3_HUMAN (1-355): 3.49e-72: 230: 58.03
+	Hs
		134356 CCL4_HUMAN (1-92): 1.69e-37: 122: 76.09		ACKR2_HUMAN (16-313): 4.77e-53: 181: 39.74
+	Hs
		134400 CCL13_HUMAN (1-91): 2.11e-37: 122: 39.56		ACKR2_HUMAN (16-313): 4.77e-53: 181: 39.74
+	Hs
		134380 CCL14_HUMAN (1-92): 1.14e-35: 118: 45.16		ACKR2_HUMAN (16-313): 4.77e-53: 181: 39.74
+	Hs
		526561 CCL4_HUMAN (1-92): 1.69e-37: 122: 76.09		CXCR5_HUMAN (31-318): 4.65e-46: 162: 32.65
+	Hs
		830629 CCL13_HUMAN (1-91): 2.11e-37: 122: 39.56		CXCR3_HUMAN (13-315): 4.66e-44: 157: 32.92
+	Mm
		139696 CCL2_MOUSE (1-92): 1.22e-34: 117: 38.71		ACKR2_MOUSE (7-313): 1.17e-45: 161: 35.44