HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: TRI29 (Q14134)
Tripartite motif-containing protein 29 (Ataxia telangiectasia group D-associated protein)
Gene: TRIM29

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.845

Property	Details
Experiments	26496610, 11331580, 20211142
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid array
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	zf-B_box~zf-B_box
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0008270 - zinc ion binding GO:0045087 - innate immune response
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 588
+	Hs
		536726 TRI27_HUMAN (1-513): 0: 523: 100.00		RO52_HUMAN (140-588): 2.7e-92: 293: 16.74
+	Hs
		536980 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI11_HUMAN (148-488): 3.8e-82: 267: 15.97
+	Hs
		536717 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI27_HUMAN (140-503): 7.63e-79: 259: 14.42
+	Hs
		536970 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI43_HUMAN (148-477): 5.9e-76: 250: 17.15
+	Hs
		584870 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		RO52_HUMAN (140-588): 2.7e-92: 293: 16.74
+	Hs
		175635 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI18_HUMAN (95-418): 6.17e-66: 229: 20.85
+	Hs
		537123 TRI27_HUMAN (1-513): 0: 523: 100.00		TRIM1_HUMAN (91-432): 5.04e-65: 228: 17.42
+	Hs
		537045 TRI27_HUMAN (1-513): 0: 523: 100.00		TRIM8_HUMAN (171-531): 3.4e-66: 227: 18.43
+	Hs
		585058 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRIM5_HUMAN (140-533): 1.09e-83: 271: 17.10
+	Hs
		262150 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRIM3_HUMAN (136-566): 5.8e-77: 260: 15.75
+	Hs
		585075 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRI39_HUMAN (148-531): 5.93e-79: 260: 14.75
+	Hs
		1336382 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		TRI39_HUMAN (148-531): 5.93e-79: 260: 14.75
+	Mm
		1112402 RO52_MOUSE (3-492): 8.38e-148: 433: 34.55		Q3U7K7_MOUSE (143-534): 4.37e-87: 279: 15.80
+	Hs
		536904 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI50_HUMAN (168-412): 1.08e-49: 181: 18.65
+	Hs
		585056 RO52_HUMAN (1-500): 2.33e-160: 465: 36.78		TRIM8_HUMAN (171-531): 3.4e-66: 227: 18.43
+	Hs
		1318352 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		TRIM8_HUMAN (171-531): 3.4e-66: 227: 18.43
+	Hs
		536913 TRI27_HUMAN (1-513): 0: 523: 100.00		TRI42_HUMAN (151-383): 7.89e-43: 165: 19.57
+	Hs
		1336392 TRI39_HUMAN (7-494): 3.22e-158: 462: 37.60		TRI17_HUMAN (145-459): 5.99e-64: 219: 15.59