HitPredict

Interactor 1: TRI27 (P14373)
Zinc finger protein RFP (EC 2.3.2.27) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: TRIM27

Interactor 2: TAB3 (Q8N5C8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (NF-kappa-B-activating protein 1) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3)
Gene: TAB3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32343849
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008270 - zinc ion binding GO:0010507 - negative regulation of autophagy
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 712
+	Hs
		135034 TRI38_HUMAN (1-494): 7.99e-134: 397: 32.40		TAB3_HUMAN (1-712): 8.19e-99: 321: 100.00
+	Hs
		537101 TRI27_HUMAN (1-513): 0: 523: 100.00		TAB2_HUMAN (1-711): 6.6e-48: 182: 30.53
+	Hs
		1234340 TRIM5_HUMAN (1-494): 9.4e-127: 380: 29.15		TAB3_HUMAN (1-712): 8.19e-99: 321: 100.00
+	Mm
		548982 TR30A_MOUSE (1-494): 1.14e-111: 341: 24.62		TAB3_MOUSE (1-712): 2.53e-96: 315: 94.69
+	Hs
		537122 TRI27_HUMAN (1-513): 0: 523: 100.00		MAGL2_HUMAN (48-676): 3.64e-10: 65.6: 9.89
+	Hs
		135043 TRI38_HUMAN (1-494): 7.99e-134: 397: 32.40		TAB2_HUMAN (1-711): 6.6e-48: 182: 30.53
+	Hs
		1223392 TRI22_HUMAN (1-494): 2.57e-131: 392: 29.12		TAB2_HUMAN (1-711): 6.6e-48: 182: 30.53
+	Hs
		1318714 TRIM5_HUMAN (1-494): 9.4e-127: 380: 29.15		TAB2_HUMAN (1-711): 6.6e-48: 182: 30.53
+	Mm
		548987 TR30A_MOUSE (1-494): 1.14e-111: 341: 24.62		TAB2_MOUSE (1-711): 4.55e-45: 173: 28.09
+	Hs
		554346 BT2A2_HUMAN (303-497): 3.02e-57: 200: 49.75		MUC1_HUMAN (54-680): 4.91e-23: 107: 9.24