Interactor 1: DRD2 (P14416)
D(2) dopamine receptor (Dopamine D2 receptor)
Gene: DRD2
Interactor 2: ARRB2 (P32121)
Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3)
Gene: ARRB2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32450252 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~Arrestin_C, 7tm_1~Arrestin_N |
| Common GO terms | GO:0001933 - negative regulation of protein phosphorylation GO:0002031 - G protein-coupled receptor internalization GO:0002092 - positive regulation of receptor internalization GO:0005886 - plasma membrane GO:0007628 - adult walking behavior and 5 others more... |
| Homologous interactions | 7 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
