Interactor 1: LIN12 (P14585)
Protein lin-12 (Abnormal cell lineage protein 12) (Notch-like protein lin-12) [Cleaved into: lin-12/Notch intracellular domain]
Gene: lin-12

Interactor 2: LAG2 (P45442)
Protein lag-2 (Lethal protein 461)
Gene: lag-2

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 18700817
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~EGF, DSL~EGF_CA, EGF~EGF_CA
Common GO terms GO:0001708 - cell fate specification
GO:0002119 - nematode larval development
GO:0005112 - Notch binding
GO:0005886 - plasma membrane
GO:0007219 - Notch signaling pathway
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1429
Ce

1 402
+ Ce
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Mm
+ Dr
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024