Protein: UBS3A
Ubiquitin-associated and SH3 domain-containing protein A (Cbl-interacting protein 4) (CLIP4) (Suppressor of T-cell receptor signaling 2) (STS-2) (T-cell ubiquitin ligand 1) (TULA-1)

Gene: UBS3A, UBASH3A
Organism: Homo sapiens
Interactions: 130
UniProt ID: P57075

Gene Ontology (top 5):
GO:0001817 - regulation of cytokine production
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016607 - nuclear speck

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

507742

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

4

14

Small-scale

0.893

High

241229

PRKN
E3 ubiquitin-protein ligase parkin

3

11

Small-scale

0.857

High

943761

ASPP2
Apoptosis-stimulating of p53 protein 2

2

12

High-throughput

0.817

High

363053

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.754

High

213879

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

10

Small-scale

0.724

High

651242

CBL
E3 ubiquitin-protein ligase CBL

5

20

Small-scale

0.713

High

943765

DAZP2
DAZ-associated protein 2

4

2

High-throughput

0.703

High

943810

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

5

High-throughput

0.698

High

855568

CRK
Adapter molecule crk

1

20

High-throughput

0.691

High

221106

SPY2
Protein sprouty homolog 2

3

14

High-throughput

0.674

High

943760

CBLB
E3 ubiquitin-protein ligase CBL-B

3

20

Small-scale

0.672

High

570391

GFAP
Glial fibrillary acidic protein

3

20

High-throughput

0.667

High

943821

FGOP2
FGFR1 oncogene partner 2

3

0

High-throughput

0.639

High

943787

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

19

High-throughput

0.621

High

834162

CSK
Tyrosine-protein kinase CSK

1

20

High-throughput

0.618

High

849059

ZAP70
Tyrosine-protein kinase ZAP-70

1

20

Small-scale

0.618

High

943747

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

1

17

Small-scale

0.618

High

943799

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

17

High-throughput

0.618

High

943829

ALK
ALK tyrosine kinase receptor

1

20

Small-scale

0.618

High

74334

ZBT42
Zinc finger and BTB domain-containing protein 42

2

3

High-throughput

0.606

High

133649

WASL
Actin nucleation-promoting factor WASL

2

20

High-throughput

0.606

High

221332

SPY1
Protein sprouty homolog 1

2

14

High-throughput

0.606

High

294848

BCAR3
Breast cancer anti-estrogen resistance protein 3

2

20

High-throughput

0.606

High

385075

K1C14
Keratin, type I cytoskeletal 14

2

20

High-throughput

0.606

High

571911

TRI27
Zinc finger protein RFP

2

9

High-throughput

0.606

High

842628

WASP
Actin nucleation-promoting factor WAS

2

20

High-throughput

0.606

High

896715

DYN2
Dynamin-2

2

16

High-throughput

0.606

High

943753

NGAL
Neutrophil gelatinase-associated lipocalin

2

2

High-throughput

0.606

High

943757

SOS1
Son of sevenless homolog 1

2

18

High-throughput

0.606

High

943764

K1H2
Keratin, type I cuticular Ha2

2

20

High-throughput

0.606

High

943766

K1H1
Keratin, type I cuticular Ha1

2

20

High-throughput

0.606

High

943772

KPRP
Keratinocyte proline-rich protein

2

2

High-throughput

0.606

High

943777

K1C39
Keratin, type I cytoskeletal 39

2

20

High-throughput

0.606

High

943784

KCTD1
BTB/POZ domain-containing protein KCTD1

2

10

High-throughput

0.606

High

943791

TAXB1
Tax1-binding protein 1

2

18

High-throughput

0.606

High

943792

TRI50
E3 ubiquitin-protein ligase TRIM50

2

9

High-throughput

0.606

High

943793

ARRD1
Arrestin domain-containing protein 1

2

1

High-throughput

0.606

High

943796

DTX3
Probable E3 ubiquitin-protein ligase DTX3

2

6

High-throughput

0.606

High

943798

LNX1
E3 ubiquitin-protein ligase LNX

2

12

High-throughput

0.606

High

943804

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.606

High

943807

ARRD3
Arrestin domain-containing protein 3

2

1

High-throughput

0.606

High

943809

DDT4L
DNA damage-inducible transcript 4-like protein

2

1

High-throughput

0.606

High

943812

LZTS2
Leucine zipper putative tumor suppressor 2

2

20

High-throughput

0.606

High

943813

TRIM8
E3 ubiquitin-protein ligase TRIM8

2

15

High-throughput

0.606

High

943814

TRIM5
Tripartite motif-containing protein 5

2

9

High-throughput

0.606

High

943815

P63
Tumor protein 63

2

1

High-throughput

0.606

High

943817

SLAP2
Src-like-adapter 2

2

20

High-throughput

0.606

High

943818

VP37B
Vacuolar protein sorting-associated protein 37B

2

18

High-throughput

0.606

High

943820

DISC1
Disrupted in schizophrenia 1 protein

2

1

High-throughput

0.606

High

943822

RN216
E3 ubiquitin-protein ligase RNF216

2

4

High-throughput

0.606

High

943825

ZRAN1
Ubiquitin thioesterase ZRANB1

2

8

High-throughput

0.606

High

943826

MKRN1
E3 ubiquitin-protein ligase makorin-1

2

2

High-throughput

0.606

High

943828

ISY1
Pre-mRNA-splicing factor ISY1 homolog

2

4

High-throughput

0.606

High

943831

LZTS1
Leucine zipper putative tumor suppressor 1

2

20

High-throughput

0.606

High

943833

WBP11
WW domain-binding protein 11

2

11

High-throughput

0.606

High

771869

CBS
Cystathionine beta-synthase

2

0

High-throughput

0.601

High

943755

DYN1
Dynamin-1

2

16

Small-scale

0.601

High

943756

Q05BL1
TP53BP2 protein

1

8

High-throughput

0.594

High

943800

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

1

0

Small-scale

0.586

High

943779

SNR48
U11/U12 small nuclear ribonucleoprotein 48 kDa protein

2

0

High-throughput

0.580

High

943781

NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor

2

0

High-throughput

0.580

High

943790

FA83A
Protein FAM83A

2

0

High-throughput

0.580

High

943797

SMIP6
Sperm microtubule inner protein 6

2

0

High-throughput

0.580

High

943803

CSN9
COP9 signalosome complex subunit 9

2

0

High-throughput

0.580

High

943824

ZN219
Zinc finger protein 219

2

0

High-throughput

0.580

High

323258

TRI37
E3 ubiquitin-protein ligase TRIM37

1

17

High-throughput

0.573

High

943754

REL
Proto-oncogene c-Rel

1

5

High-throughput

0.573

High

943767

SF3B4
Splicing factor 3B subunit 4

1

6

High-throughput

0.573

High

943776

K1C40
Keratin, type I cytoskeletal 40

1

20

High-throughput

0.573

High

851278

PRS6B
26S proteasome regulatory subunit 6B

1

2

Small-scale

0.561

High

943816

RNF41
E3 ubiquitin-protein ligase NRDP1

1

15

Small-scale

0.561

High

65027

GG6L9
Golgin subfamily A member 6-like protein 9

2

20

High-throughput

0.553

High

175971

N4BP3
NEDD4-binding protein 3

2

20

High-throughput

0.553

High

943771

ZC21C
Zinc finger C2HC domain-containing protein 1C

2

1

High-throughput

0.553

High

943780

ZN474
Zinc finger protein 474

2

1

High-throughput

0.553

High

943783

K0408
Uncharacterized protein KIAA0408

2

2

High-throughput

0.553

High

943801

TEKT4
Tektin-4

2

7

High-throughput

0.553

High

943805

TEKT1
Tektin-1

2

7

High-throughput

0.553

High

943811

PNMA5
Paraneoplastic antigen-like protein 5

2

5

High-throughput

0.553

High

943819

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

1

High-throughput

0.553

High

943832

DLGP4
Disks large-associated protein 4

2

13

High-throughput

0.553

High

617286

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

2

High-throughput

0.541

High

856229

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.541

High

943758

SOS2
Son of sevenless homolog 2

1

17

High-throughput

0.541

High

943759

DLG1
Disks large homolog 1

1

7

High-throughput

0.541

High

943762

PDE7A
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A

1

1

High-throughput

0.541

High

943785

TAOK1
Serine/threonine-protein kinase TAO1

1

11

High-throughput

0.541

High

249337

ZIC3
Zinc finger protein ZIC 3

1

0

High-throughput

0.518

High

943769

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

0

High-throughput

0.518

High

943786

CXXC5
CXXC-type zinc finger protein 5

1

0

High-throughput

0.518

High

943827

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.518

High

943763

DCTN1
Dynactin subunit 1

1

13

High-throughput

0.515

High

943789

Q7Z783
Protein sprouty homolog 2

1

14

High-throughput

0.515

High

943834

RNF11
RING finger protein 11

1

3

High-throughput

0.515

High

461322

HS90A
Heat shock protein HSP 90-alpha

1

9

Small-scale

0.501

High

532487

CH60
60 kDa heat shock protein, mitochondrial

1

4

Small-scale

0.501

High

573408

ENPL
Endoplasmin

1

9

Small-scale

0.501

High

934345

TERA
Transitional endoplasmic reticulum ATPase

1

5

Small-scale

0.501

High

943751

PRS4
26S proteasome regulatory subunit 4

1

2

Small-scale

0.501

High

943752

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

7

Small-scale

0.501

High

943770

TBB8
Tubulin beta-8 chain

1

5

Small-scale

0.501

High

943835

NEMO
NF-kappa-B essential modulator

1

12

Small-scale

0.501

High

130935

HIP1
Huntingtin-interacting protein 1

1

6

Small-scale

0.479

High

348446

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

Small-scale

0.479

High

600782

HSP76
Heat shock 70 kDa protein 6

1

7

Small-scale

0.479

High

761612

HSP74
Heat shock 70 kDa protein 4

1

8

Small-scale

0.479

High

943748

ACTB
Actin, cytoplasmic 1

1

20

Small-scale

0.479

High

943773

CE350
Centrosome-associated protein 350

1

13

High-throughput

0.479

High

943778

Q6FHJ6
Potassium voltage-gated channel subfamily E member 1

1

1

High-throughput

0.470

High

635844

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

Small-scale

0.458

High

943749

ABCE1
ATP-binding cassette sub-family E member 1

1

0

Small-scale

0.458

High

943775

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.445

High

583933

KCNE1
Potassium voltage-gated channel subfamily E member 1

1

1

High-throughput

0.439

High

943794

CCD33
Coiled-coil domain-containing protein 33

1

1

High-throughput

0.439

High

221549

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

2

0

High-throughput

0.316

High

286639

STX11
Syntaxin-11

2

0

High-throughput

0.316

High

943782

SHSA6
Protein shisa-6

2

0

High-throughput

0.316

High

943788

TMCO2
Transmembrane and coiled-coil domain-containing protein 2

2

0

High-throughput

0.316

High

943795

FADS6
Fatty acid desaturase 6

2

0

High-throughput

0.316

High

943802

TM239
Transmembrane protein 239

2

0

High-throughput

0.316

High

943806

PMEPA
Protein TMEPAI

2

0

High-throughput

0.316

High

943808

PKHB2
Pleckstrin homology domain-containing family B member 2

2

0

High-throughput

0.316

High

460252

CD3E
T-cell surface glycoprotein CD3 epsilon chain

1

0

Small-scale

0.292

High

877612

B3A3
Anion exchange protein 3

1

0

High-throughput

0.282

High

943750

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.282

High

943768

NDF2
Neurogenic differentiation factor 2

1

0

High-throughput

0.282

High

943774

SPRY7
SPRY domain-containing protein 7

1

0

High-throughput

0.282

High

943823

CUED1
CUE domain-containing protein 1

1

0

High-throughput

0.282

High

943830

SSRG
Translocon-associated protein subunit gamma

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025