HitPredict

Interactor 1: NCF1 (P14598)
Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)
Gene: NCF1

Interactor 2: SYN1 (P17600)
Synapsin-1 (Brain protein 4.1) (Synapsin I)
Gene: SYN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10899172
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030425 - dendrite
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 390 Hs			1 705
+	Mm
		292470 SH3G3_MOUSE (160-288): 3.32e-18: 86.7: 11.36		SYN1_MOUSE (1-705): 2.33e-173: 514: 96.03
+	Hs
		568524 ITSN2_HUMAN (8-390): 2.54e-15: 80.2: 11.00		SYN1_HUMAN (1-705): 2.23e-169: 504: 100.00
+	Dm
		112573 M9ND00_DROME (93-384): 4.02e-26: 112: 15.15		SYN_DROME (60-666): 9.17e-127: 403: 33.28
+	Hs
		203224 MYO1E_HUMAN (3-283): 4.56e-53: 191: 15.20		SYNJ1_HUMAN (290-705): 2.31e-41: 165: 16.89
+	Hs
		203208 NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16		SYNJ1_HUMAN (290-705): 2.31e-41: 165: 16.89
+	Hs
		203249 SH3G2_HUMAN (6-211): 5.16e-32: 125: 10.68		SYNJ1_HUMAN (290-705): 2.31e-41: 165: 16.89
+	Hs
		203192 SRBS2_HUMAN (163-283): 1.9e-20: 95.7: 21.15		SYNJ1_HUMAN (290-705): 2.31e-41: 165: 16.89
+	Hs
		1021688 MYO1E_HUMAN (3-283): 4.56e-53: 191: 15.20		CBP_HUMAN (394-705): 4.92e-11: 68.8: 14.97
+	Hs
		203230 SH319_HUMAN (81-282): 8.99e-15: 77.9: 17.83		SYNJ1_HUMAN (290-705): 2.31e-41: 165: 16.89
+	Hs
		557745 NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16		RIN3_HUMAN (331-697): 1.74e-23: 108: 13.47
+	Hs
		70370 B2R6S4_HUMAN (130-350): 8.06e-34: 131: 17.16		RIN3_HUMAN (331-697): 1.74e-23: 108: 13.47
+	Hs
		846969 SRC8_HUMAN (4-282): 7.5e-33: 131: 12.67		SMCA4_HUMAN (369-705): 1.59e-23: 108: 15.92
+	Mm
		101448 SH3G1_MOUSE (6-218): 8.41e-32: 125: 11.95		F8VPR5_MOUSE (381-685): 3.31e-21: 101: 15.08
+	Hs
		1307434 SH3G2_HUMAN (6-211): 5.16e-32: 125: 10.68		PTN23_HUMAN (336-691): 3.68e-20: 98.1: 16.75
+	Hs
		1251932 ITSN2_HUMAN (8-390): 2.54e-15: 80.2: 11.00		RIN3_HUMAN (331-697): 1.74e-23: 108: 13.47
+	Hs
		1126375 SH319_HUMAN (81-282): 8.99e-15: 77.9: 17.83		PTN23_HUMAN (336-691): 3.68e-20: 98.1: 16.75
+	Rn
		192744 SRBS2_RAT (163-283): 2.18e-21: 98.4: 21.15		SYNJ1_RAT (336-704): 6e-10: 65: 13.91
+	Mm
		88460 SH3G3_MOUSE (160-288): 3.32e-18: 86.7: 11.36		D3Z656_MOUSE (346-690): 8.34e-12: 71.1: 11.71
+	Rn
		192356 SH3G3_RAT (222-285): 5.77e-18: 86.3: 12.50		SYNJ1_RAT (336-704): 6e-10: 65: 13.91
+	Hs
		257713 ITSN2_HUMAN (8-390): 2.54e-15: 80.2: 11.00		ANR17_HUMAN (380-654): 5.65e-09: 61.9: 12.73