HitPredict

Interactor 1: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Interactor 2: HDAC6 (Q9UBN7)
Protein deacetylase HDAC6 (EC 3.5.1.-) (E3 ubiquitin-protein ligase HDAC6) (EC 2.3.2.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23703321
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019899 - enzyme binding GO:0034605 - cellular response to heat
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 1215
+	Hs
		1198800 Q53FC7_HUMAN (1-643): 0: 965: 99.22		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		761528 HS71L_HUMAN (1-643): 0: 959: 79.32		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		538048 HSP7C_HUMAN (4-615): 0: 937: 79.25		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		931144 HSP72_HUMAN (3-643): 0: 923: 77.45		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		600807 HSP76_HUMAN (1-643): 0: 970: 100.00		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		537113 HSP7C_HUMAN (4-615): 0: 937: 79.25		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		537631 HSP7C_HUMAN (4-615): 0: 937: 79.25		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Hs
		537657 HSP7C_HUMAN (4-615): 0: 937: 79.25		HDA10_HUMAN (85-449): 7.65e-153: 475: 53.53
+	Hs
		536843 HSP7C_HUMAN (4-615): 0: 937: 79.25		HDAC4_HUMAN (405-873): 3.54e-147: 473: 36.51
+	Hs
		537592 HSP7C_HUMAN (4-615): 0: 937: 79.25		HDAC7_HUMAN (440-891): 1.81e-147: 470: 36.44
+	Hs
		188157 HSP7C_HUMAN (4-615): 0: 937: 79.25		HDAC3_HUMAN (479-890): 1.13e-146: 450: 18.29
+	Dm
		538247 HSP7D_DROME (4-614): 0: 922: 79.38		Q86NK9_DROME (1093-1215): 1.32e-41: 168: 45.97