HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: KCD15 (Q96SI1)
BTB/POZ domain-containing protein KCTD15 (Potassium channel tetramerization domain-containing protein 15)
Gene: KCTD15

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	29665387, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 283
+	Mm
		989265 HSP7C_MOUSE (1-646): 0: 965: 99.85		BACD1_MOUSE (18-213): 4.93e-52: 174: 22.84
+	Hs
		538030 HSP7C_HUMAN (1-646): 0: 966: 100.00		KCND2_HUMAN (35-205): 1.36e-46: 166: 20.47
+	Hs
		761465 HS71L_HUMAN (2-646): 0: 964: 82.48		BACD1_HUMAN (36-213): 1.96e-48: 165: 24.02
+	Mm
		1223257 HS71A_MOUSE (1-646): 0: 952: 83.59		BACD1_MOUSE (18-213): 4.93e-52: 174: 22.84
+	Hs
		537128 HSP7C_HUMAN (1-646): 0: 966: 100.00		BACD2_HUMAN (36-228): 1.05e-46: 160: 21.65
+	Hs
		761396 HS71L_HUMAN (2-646): 0: 964: 82.48		BACD2_HUMAN (36-228): 1.05e-46: 160: 21.65
+	Hs
		600809 HSP76_HUMAN (6-646): 0: 954: 77.54		BACD2_HUMAN (36-228): 1.05e-46: 160: 21.65
+	Mm
		602294 HSP72_MOUSE (2-612): 0: 935: 87.77		BACD1_MOUSE (18-213): 4.93e-52: 174: 22.84
+	Hs
		930994 HSP72_HUMAN (2-646): 0: 938: 85.47		KCD17_HUMAN (56-193): 3.43e-42: 148: 29.71
+	Hs
		931177 HSP72_HUMAN (2-646): 0: 938: 85.47		KCTD3_HUMAN (48-188): 5.25e-39: 146: 30.77