HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27248496, 31353912
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0019899 - enzyme binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 626
+	Hs
		537557 HSP7C_HUMAN (1-646): 0: 966: 100.00		COP1_HUMAN (154-619): 7.57e-71: 245: 14.96
+	Hs
		600871 HSP76_HUMAN (6-646): 0: 954: 77.54		COP1_HUMAN (154-619): 7.57e-71: 245: 14.96
+	Hs
		537653 HSP7C_HUMAN (1-646): 0: 966: 100.00		FBXW7_HUMAN (247-571): 4.45e-61: 217: 13.72
+	Hs
		931011 HSP72_HUMAN (2-646): 0: 938: 85.47		COP1_HUMAN (154-619): 7.57e-71: 245: 14.96
+	Hs
		537090 HSP7C_HUMAN (1-646): 0: 966: 100.00		ERCC8_HUMAN (305-532): 1.36e-57: 200: 19.92
+	Hs
		537452 HSP7C_HUMAN (1-646): 0: 966: 100.00		WDR5B_HUMAN (395-624): 5.48e-51: 181: 11.74
+	Hs
		537531 HSP7C_HUMAN (1-646): 0: 966: 100.00		POC1A_HUMAN (391-623): 3.95e-49: 178: 12.45
+	Hs
		761452 HS71L_HUMAN (2-646): 0: 964: 82.48		POC1A_HUMAN (391-623): 3.95e-49: 178: 12.45
+	Hs
		930875 HSP72_HUMAN (2-646): 0: 938: 85.47		ERCC8_HUMAN (305-532): 1.36e-57: 200: 19.92
+	Hs
		600864 HSP76_HUMAN (6-646): 0: 954: 77.54		POC1A_HUMAN (391-623): 3.95e-49: 178: 12.45
+	Hs
		536889 HSP7C_HUMAN (1-646): 0: 966: 100.00		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Dm
		538293 HSP7D_DROME (1-612): 0: 936: 86.60		FBXW7_DROME (479-626): 2.97e-23: 107: 18.00
+	Hs
		536681 HSP7C_HUMAN (1-646): 0: 966: 100.00		LIS1_HUMAN (524-623): 3.63e-12: 70.5: 11.00
+	Dm
		1012151 HSP70_DROME (5-646): 0: 925: 74.81		FBXW7_DROME (479-626): 2.97e-23: 107: 18.00
+	Ce
		482114 HSP1_CAEEL (1-646): 0: 936: 84.39		LIN53_CAEEL (251-477): 2.76e-20: 95.7: 15.73