Interactor 1: RAD4 (P14736)
DNA repair protein RAD4
Gene: RAD4

Interactor 2: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 17882165, 11259433, 9490418, 10688190, 11805826, 9837874, 9001217, 25562780, 15601997, 9685610, 31106376, 33119737, 18387345, 16554755, 37968396, 16401726, 16429126
Identification Methods x-ray crystallography, coimmunoprecipitation, pull down, ion exchange chromatography, molecular sieving, two hybrid, tandem affinity purification, affinity chromatography technology, biochemical
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Rad4~XPC-binding
Common GO terms GO:0000111 - nucleotide-excision repair factor 2 complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000715 - nucleotide-excision repair, DNA damage recognition
GO:0003684 - damaged DNA binding
GO:0005737 - cytoplasm
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 754
Sc

1 398
+ Sc
+ Sp
+ Hs
+ Hs
+ Mm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024