Interactor 1: EI2BA (P14741)
Translation initiation factor eIF2B subunit alpha (GCD complex subunit GCN3) (Guanine nucleotide exchange factor subunit GCN3) (Translational activator GCN3) (eIF2B GDP-GTP exchange factor subunit alpha)
Gene: GCN3

Interactor 2: EI2BA (P14741)
Translation initiation factor eIF2B subunit alpha (GCD complex subunit GCN3) (Guanine nucleotide exchange factor subunit GCN3) (Translational activator GCN3) (eIF2B GDP-GTP exchange factor subunit alpha)
Gene: GCN3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.838

The method score is based on:

Property Details
Experiments 10688190, 11283351, 18719252
Identification Methods two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IF-2B~IF-2B
Common GO terms GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005851 - eukaryotic translation initiation factor 2B complex
and 5 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 305
Sc

1 305
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Ce
+ Sc
+ Sc
+ Sp
+ Dm
+ Hs
+ Sc

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Last updated: 15 Jul 2024