Interactor 1: PIM1 (P11309)
Serine/threonine-protein kinase pim-1 (EC 2.7.11.1)
Gene: PIM1

Interactor 2: RHEB (Q15382)
GTP-binding protein Rheb (EC 3.6.5.-) (Ras homolog enriched in brain)
Gene: RHEB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments unassigned3799
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Ras
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0043539 - protein serine/threonine kinase activator activity
GO:1904263 - positive regulation of TORC1 signaling
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 313
Hs

1 184
+ Hs
+ Hs
+ Hs
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Service provided by Combinatics, Japan

Last updated: 11Aug2025