Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: CADH5 (P33151)
Cadherin-5 (7B4 antigen) (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144)
Gene: CDH5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 9434630, 33961781, 12003790
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~CADH_Y-type_LIR
Common GO terms GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0005912 - adherens junction
GO:0016342 - catenin complex
GO:0019903 - protein phosphatase binding
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 745
Hs

1 784
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+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024