HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0005912 - adherens junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 986
+	Hs
		542333 PLAK_HUMAN (1-745): 0: 551: 100.00		EPHA7_HUMAN (5-986): 0: 1212: 62.37
+	Hs
		542243 PLAK_HUMAN (1-745): 0: 551: 100.00		EPHA5_HUMAN (2-986): 0: 1201: 63.67
+	Hs
		717105 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		EPHA7_HUMAN (5-986): 0: 1212: 62.37
+	Hs
		542198 PLAK_HUMAN (1-745): 0: 551: 100.00		EPHB2_HUMAN (30-983): 0: 1169: 58.47
+	Hs
		716907 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		EPHA5_HUMAN (2-986): 0: 1201: 63.67
+	Hs
		665553 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		EPHB2_HUMAN (30-983): 0: 1169: 58.47
+	Hs
		665443 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		EPHA8_HUMAN (30-981): 0: 1107: 57.11
+	Hs
		239093 CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25		EPHA4_HUMAN (1-986): 0: 1293: 100.00
+	Hs
		665156 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		EPHA2_HUMAN (27-986): 0: 1059: 50.36
+	Hs
		239138 CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25		EPHA7_HUMAN (5-986): 0: 1212: 62.37
+	Dm
		578636 ARM_DROME (2-730): 6.94e-161: 488: 60.33		Q0KIF4_DROME (25-974): 0: 894: 41.08
+	Mm
		546270 PLAK_MOUSE (1-745): 0: 553: 98.39		INSR_MOUSE (284-952): 1.38e-146: 472: 24.38
+	Hs
		542203 PLAK_HUMAN (1-745): 0: 551: 100.00		UFO_HUMAN (268-928): 5.13e-150: 469: 23.72
+	Hs
		435524 PLAK_HUMAN (1-745): 0: 551: 100.00		IGF1R_HUMAN (394-884): 1.97e-137: 447: 29.47
+	Rn
		544931 CTNB1_RAT (1-731): 1.13e-173: 519: 67.38		INSR_RAT (284-952): 7.97e-144: 465: 24.14
+	Hs
		435557 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		IGF1R_HUMAN (394-884): 1.97e-137: 447: 29.47
+	Hs
		412054 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		FYN_HUMAN (615-879): 2.51e-66: 234: 44.20
+	Hs
		522819 CTNB1_HUMAN (1-731): 1.58e-173: 519: 67.38		SRC_HUMAN (601-871): 2.14e-64: 229: 45.42
+	Hs
		239024 CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25		FYN_HUMAN (615-879): 2.51e-66: 234: 44.20
+	Hs
		239035 CTND1_HUMAN (203-728): 3.14e-90: 305: 16.25		SRC_HUMAN (601-871): 2.14e-64: 229: 45.42