Interactor 1: TOP2A (P11388)
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)
Gene: TOP2A
Interactor 2: HMGA2 (P52926)
High mobility group protein HMGI-C (High mobility group AT-hook protein 2)
Gene: HMGA2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 0.60 | 0.515 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 36835656 |
| Identification Methods | proximity labelling technology, affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001673 - male germ cell nucleus GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization GO:0008301 - DNA binding, bending and 1 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
