Protein: TOP2B
DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme)

Gene: TOP2B
Organism: Mus musculus
Interactions: 12
UniProt ID: Q64511

Gene Ontology (top 5):
GO:0001764 - neuron migration
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0003916 - DNA topoisomerase activity
GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1225761

HDAC4
Histone deacetylase 4

1

4

High-throughput

0.536

High

1225767

AICDA
Single-stranded DNA cytosine deaminase

1

0

Small-scale

0.530

High

629305

PO5F1
POU domain, class 5, transcription factor 1

1

1

High-throughput

0.479

High

1194878

TET2
Methylcytosine dioxygenase TET2

1

1

Small-scale

0.479

High

1225474

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

1

High-throughput

0.479

High

1225762

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

12

Small-scale

0.479

High

1225763

FACD2
Fanconi anemia group D2 protein homolog

1

3

High-throughput

0.479

High

1225764

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.479

High

1225765

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

11

Small-scale

0.479

High

1225766

ELF5
ETS-related transcription factor Elf-5

1

1

High-throughput

0.479

High

392

AUTS2
Autism susceptibility gene 2 protein homolog

1

1

Small-scale

0.445

High

915622

HMGA2
High mobility group protein HMGI-C

1

2

High-throughput

0.445

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025