HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: RPB3 (P16370)
DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (B44.5) (DNA-directed RNA polymerase II 45 kDa polypeptide)
Gene: RPB3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.587

Property	Details
Experiments	16554755, 19536198, 15766533
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 318
+	Sc
		365729 HSP82_YEAST (1-705): 0: 968: 95.63		RPB3_YEAST (1-318): 3.91e-173: 484: 100.00
+	Hs
		169770 HS90B_HUMAN (5-705): 0: 1022: 61.15		RPAC1_HUMAN (3-268): 1.5e-104: 311: 25.16
+	Ca
		804513 HSP90_CANAL (4-705): 0: 953: 82.36		Q5A462_CANAL (2-313): 1.17e-130: 376: 55.21
+	Sc
		365593 HSP82_YEAST (1-705): 0: 968: 95.63		RPAC1_YEAST (3-258): 3.25e-89: 271: 23.31